J Korean Acad Fam Med.  2007 Jun;28(6):460-465.

A Case Report of Amiodarone-induced Multiple Toxicity after a Long Course of a Low Dose Therapy

Affiliations
  • 1Department of Family Medicine, Hanyang University College of Medicine, Seoul, Korea. fmhwang@hanyang.ac.kr
  • 2Department of Diagnostic Radiology, Hanyang University College of Medicine, Seoul, Korea.

Abstract

Amiodarone is a potent antiarrhythmic agent that is used to treat ventricular arrhythmias and atrial fibrillation. But it has a wide range of adverse effects, including pulmonary toxicity, thyroid dysfunction, liver toxicity, gastrointestinal events, corneal deposits, peripheral neuropathy and so on. Patients treated with amiodarone should be followed regularly to assess ongoing need for amiodarone, efficacy of the drug, appropriateness of dosage, adverse effects, and potential drug interactions. We experienced a case of severe weight loss due to amiodarone-induced multiple toxicity after a long course of a low dose therapy. So we report this unusual case with literature review.

Keyword

amiodarone; adverse effects; pulmonary toxicity; thyrotoxicosis; anorexia; weight loss

MeSH Terms

Amiodarone
Anorexia
Arrhythmias, Cardiac
Atrial Fibrillation
Drug Interactions
Humans
Liver Diseases
Peripheral Nervous System Diseases
Thyroid Gland
Thyrotoxicosis
Weight Loss
Amiodarone
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