Korean J Urol.  2006 May;47(5):556-558. 10.4111/kju.2006.47.5.556.

A Young Man with Primary Small Cell Carcinoma of the Urinary Bladder

Affiliations
  • 1Departments of Urology and Pathology, Chungbuk National University College of Medicine, Cheongju, Korea. wjkim@chungbuk.ac.kr

Abstract

Small cell carcinoma of the urinary bladder is a rare finding. It is characterized by an aggressive clinical course with early metastasis and it tends to affect the elderly who have significant comorbidities. The mean age of these patients is 67.8 years. The prognosis of small cell carcinoma of the urinary bladder is poor because its behavior is more aggressive than bladder transitional cell carcinoma. On the pathologic finding, small cell carcinoma of the urinary bladder is usually combined with transitional cell carcinoma or adenocarcinoma in approximately 40% of cases. We reported here on a case of the primary pure small cell carcinoma of the urinary bladder in a 26 year-old man who was managed with partial cystectomy and combined chemotherapy using cisplatin.

Keyword

Small cell carcinoma; Bladder

MeSH Terms

Adenocarcinoma
Adult
Aged
Carcinoma, Small Cell*
Carcinoma, Transitional Cell
Cisplatin
Comorbidity
Cystectomy
Drug Therapy
Humans
Neoplasm Metastasis
Prognosis
Urinary Bladder*
Cisplatin

Figure

  • Fig. 1 Computed tomography scan shows a 4×4cm sized intravesical polypoid mass with internal calcification in the urinary bladder. *shows a heterogenous enhancing mass protruding from the anterior bladder wall into the intravesical cavity.

  • Fig. 2 Gross finding of the tumor specimen shows a well-marginated mass.

  • Fig. 3 (A) The tumor consists of small, rather uniform cells with nuclear molding, scant cytoplasm and inconspicuous nucleoli. Frequent mitoses are observed (HE, ×400). (B) The tumor cells show positive immunoreactivity for synaptophysin (Immunohistochemistry, ×400).


Cited by  1 articles

Primary Neuroendocrine Carcinoma of the Urethra
Jun Nyung Lee, Dong Woo Lee, Young Su Kim, Ghil Suk Yoon, Jae Soo Kim, Eun Sang Yoo, Bup Wan Kim
Korean J Urol. 2008;49(3):284-286.    doi: 10.4111/kju.2008.49.3.284.


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