Korean J Urol.  2003 Sep;44(9):934-936.

Clear Cell Adenocarcinoma of the Urinary Bladder

Affiliations
  • 1Department of Urology, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea. rjpark@uuh.ulsan.kr
  • 2Department of Pathology, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea.

Abstract

A case of a clear cell carcinoma of the urinary bladder is reported. A 48-year-old female was referred to our hospital complaining of gross hematuria and terminal dysuria. She had a nodular tumor, 3x4cm in diameter, located on the bladder neck, trigone and posterior urethra. The patient underwent anterior pelvic exenteration and urinary diversion with an ileal conduit. A histopathological examination revealed a tumor composed of cells with eosinophilic cytoplasm, and partly of cells with clear cytoplasm or hobnail-shaped cells, arranged in tubular and papillary architectures. This showed the findings of a clear cell adenocarcinoma of the bladder and urethra. The patient underwent 6 courses of adjuvant chemotherapy with cisplatin and 5-FU. The patient shows no evidence of recurrence or metastasis at the 8 month postoperative follow-up.

Keyword

Clear cell adenocarcinoma; Bladder; Female

MeSH Terms

Adenocarcinoma, Clear Cell*
Chemotherapy, Adjuvant
Cisplatin
Cytoplasm
Dysuria
Eosinophils
Female
Fluorouracil
Follow-Up Studies
Hematuria
Humans
Middle Aged
Neck
Neoplasm Metastasis
Pelvic Exenteration
Recurrence
Urethra
Urinary Bladder*
Urinary Diversion
Cisplatin
Fluorouracil
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