Korean J Thorac Cardiovasc Surg.  2001 Jan;34(1):94-96.

Lung Transplantation in ABO Compatible but Nonidentical Patients

• Yu SH
• Kim HK
• Lee DY
• Paik HC
• Shin HK
• Hong YJ
• Kim BY
• Lee ES
• Kim JY

Abstract

Lung transplantation in the treatment of end-stage emphysema has been increasing in number since the recent rise in the 5 year survival rate. For the shortage of donor lungs, the single lung transplantation or transplantation in ABO compatible, nonidentical recipients has also been increasing. The lung transplantation in compatible, nonidentical recipients show good results as with identical recipients with the proper application of immunosuppressive agents. We transplanted the left lung of a 41 year-old male donor to a 35 year-old female recipient who had been suffering from severe dyspnea due to end-stage emphysema. For postoperative immunosuppression, we applied conventional triple immunotherapy(cyclosporine, azathioprine, prednisolone) and we could suppress the rejection response of transplanted lung by adding the anti-CD3 antibody(OKT3) during the operation. The patient could be discharged without any specific problem at 18th postoperative day.

Keyword

Lung transplantation; Blood type

MeSH Terms

Adult
Azathioprine
Dyspnea
Emphysema
Female
Humans
Immunosuppression
Immunosuppressive Agents
Lung Transplantation*
Lung*
Male
Survival Rate
Tissue Donors
Azathioprine
Immunosuppressive Agents