Gut Liver.  2012 Apr;6(2):218-222.

Role of Enhanced Visibility in Evaluating Polyposis Syndromes Using a Newly Developed Contrast Image Capsule Endoscope

Affiliations
  • 1Tokyo Saiseikai Central Hospital, Tokyo, Japan.
  • 2Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan. hogata@z8.keio.ac.jp
  • 3Department of General Internal Medicine, Saitama Medical University, Saitama, Japan.
  • 4Institut Arnault Tzanck, St Laurent du Var, France.
  • 5Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.

Abstract

BACKGROUND/AIMS
A flexible spectral imaging color enhancement system was installed in new capsule software for video capsule endoscopy. Contrast image capsule endoscopy (CICE) is a novel technology using light-emitting diodes selected for the main absorption range of hemoglobin. We assessed the feasibility and diagnostic effi cacy for small bowel surveillance in patients with polyposis syndromes.
METHODS
Six patients with polyposis syndromes, four with familial adenomatous polyposis and one each with Cowden syndrome (CS) and Cronkhite-Canada syndrome (CCS) were examined using CICE. We conducted three evaluations to assess the effect on the numbers of the detected polyps; compare polyp diagnostic rates between adenoma and hamartoma; and assess polyp visibility.
RESULTS
The numbers of detected polyps and diagnostic accuracy did not differ signifi cantly between pre-contrast and contrast images. However, 50% of the adenomatous polyps displayed enhanced visibility on contrast images. CICE contrast images exhibited clearly demarcated lesions and improved the visibility of minute structures of adenomatous polyps. Hamartomatous polyp micro-structures in patients with CS and CCS were more clearly visualized on contrast than pre-contrast images.
CONCLUSIONS
CICE is an effective tool for enhancing the visibility of polyps in patients with polyposis syndrome.

Keyword

Video capsule endoscopy; Image enhanced endoscopy; Contrast image capsule endoscopy; Polyposis syndrome

MeSH Terms

Absorption
Adenoma
Adenomatous Polyposis Coli
Adenomatous Polyps
Capsule Endoscopes
Capsule Endoscopy
Hamartoma Syndrome, Multiple
Hemoglobins
Humans
Intestinal Polyposis
Polyps
Hemoglobins
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