J Biomed Transl Res.  2019 Sep;20(3):65-70. 10.12729/jbtr.2019.20.3.065.

A study on the difference of gastrointestinal transit time with minimized capsule endoscope in dogs

Affiliations
  • 1Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea. jungdi@gnu.ac.kr
  • 2College of Veterinary Medicine, Western University of Health Sciences, California 91766-1854, USA.
  • 3Section of Veterinary Research and Academic Consulting, Veteran, Inc., Seoul 06254, Korea.

Abstract

This study compares the differences in the gastrointestinal transit time between the conventional capsule endoscope and a minimized capsule endoscope model in normal dogs to verify whether the minimization of capsule endoscope can help relief retention in the gastrointestinal tract, especially in the pyloric passage. Three male beagles were used as the experimental group for which the minimized capsule endoscope model was orally administered and the control group consisted of three beagle dogs for which the conventional capsule endoscope was orally administered. Nine experiments were conducted with three experiments for each dog in each group. The results showed a significant difference in the gastric transit time (GTT) by the minimization of the capsule endoscope between the two groups (control group: 123.3 ± 80 min, experimental group: 63.3 ± 40.9 min, p=0.019). In contrast, the difference in the small bowel transit time (SBTT) by the minimization of the capsule endoscope between the two groups (control group: 86.6 ± 58.9 min, experimental group: 80 ± 33.5 min, p=0.863) was not significant. In this study, the capsule endoscopes reached the large intestine without retention in the small intestine in all subjects. The significant difference in the GTT between the control group using the conventional capsule endoscope and the experimental group using the minimized capsule endoscope model suggests that the smaller size of the capsule endoscope is helpful in resolving retention in the gastrointestinal tract, thus shorting the GTT.

Keyword

capsule endoscopy; capsule retention; dog; gastrointestinal transit time; minimization
Full Text Links
  • JBTR
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2021 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr