Korean J Pediatr.  2006 May;49(5):489-493. 10.3345/kjp.2006.49.5.489.

Risk factors and clinical characteristics of necrotizing enterocolitis in full-term newborns

• Jeoung YM
• Je HG
• Son SH

• KMID: 2278554
• DOI: http://doi.org/10.3345/kjp.2006.49.5.489

Abstract

PURPOSE: The purpose of this study was to determine those factors which could contribute to the development of necrotizing enterocolitis(NEC) in fullterm.
METHODS
We retrospectively reviewed the medical record of 20 full-terms with NEC(> or = modified Bell's staging criteria IIa) who were admitted to the Neonatal Intensive Care Unit of Il Sin Christian hospital from January 1998 through July 2005, and for each case, the next 2 healthy newborns were matched as controls.
RESULTS
Mean gestational age and birth weight in the fullterm with NEC group was 38.42 weeks and 2,915 g; in the healthy fullterm without NEC group, it was 38.61 weeks and 3,148 g. When compared with the control group, NEC infants had a significantly higher frequency of chorioamnionitis, protracted diarrhea. As for Apgar score at 1 min <7, respiratory problem, congenital heart disease. there were no differences in frequency of preeclampsia, maternal diabetes, maternal drug abuse, meconium-stained amniotic fluid, polycythemia or exchange transfusion.
CONCLUSION
Most of these full term infants have a predisposing factor before developing NEC. Our study suggested that NEC in fullterm infants was significantly associated with protracted diarrhea, and congenital heart disease.

Keyword

Necrotizing enterocolitis; Full-term newborn

MeSH Terms

Amniotic Fluid
Apgar Score
Birth Weight
Causality
Chorioamnionitis
Diarrhea
Enterocolitis, Necrotizing*
Female
Gestational Age
Heart Defects, Congenital
Humans
Infant
Infant, Newborn*
Intensive Care, Neonatal
Medical Records
Polycythemia
Pre-Eclampsia
Pregnancy
Retrospective Studies
Risk Factors*
Substance-Related Disorders