Korean J Pain.  2012 Oct;25(4):278-280. 10.3344/kjp.2012.25.4.278.

Efficacy of Stellate Ganglion Block in Cholinergic Urticaria with Acquired Generalized Hypohidrosis

• Shin JH
• Kim DW
• Yang JY
• Lee WI

• KMID: 2278172
• DOI: http://doi.org/10.3344/kjp.2012.25.4.278

Abstract

Cholinergic urticaria with acquired generalized hypohidrosis, and its pathophysiology is not well known. Autoimmunity to sweat glands or to acetylcholine receptors on sweat glands has been mentioned as one of the possible etiologies. Systemic steroid therapy, antihistamines, anticholinergics, and avoidance of the stimulatory situations are recommended for treatment. We experienced a case of cholinergic urticaria with acquired generalized hypohidrosis in a patient who had no other associated disease, and the symptoms eased after repeated bilateral stellate ganglion block. Stellate ganglion block normalized the elevated sympathetic tone and may relieve symptoms in patients with this condition.

Keyword

cholinergic urticaria; hypohidrosis; stellate ganglion block

MeSH Terms

Autoimmunity
Cholinergic Antagonists
Histamine Antagonists
Humans
Hypohidrosis
Receptors, Cholinergic
Stellate Ganglion
Sweat Glands
Urticaria
Cholinergic Antagonists
Histamine Antagonists
Receptors, Cholinergic

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