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Anaphylaxis to Chlorpheniramine Maleate and Literature Review

Choi YW, Jung MJ, Kim HO, Chung BY, Park CW

Chlorpheniramine maleate is commonly used antihistamine. Since antihistamines are the main therapeutic agents for symptomatic treatment of urticaria, anaphylaxis to antihistamines may lead to errors in diagnosis and treatment. We...
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Synergistic Effect of H1-Antihistamines on Topical Corticosteroids for Pruritus in Atopic Dermatitis: A Systematic Review and Meta-Analysis

Hur MS, Choe YB, Ahn KJ, Lee YW

BACKGROUND: Although oral antihistamines (H1-histamine receptor antagonists) are the main treatment option for pruritus in general skin dermatosis, their effect in treating pruritus of atopic dermatitis (AD) has not yet...
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Scombroid Fish Poisoning and Histamine Food Poisoning

Chung SP

Scombroid fish poisoning (SFP) is a form of histamine food poisoning caused by the ingestion of improperly stored fish. The term “scombroid” derives from the family name of the fish...
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Omalizumab as a Succesfull Therapy in Normocomplementemic Urticarial Vasculitis: A Series of Four Patients and Review of the Literature

Degirmentepe EN, Kızıltac K, Etikan P, Singer R, Memet B, Kocaturk E

Urticarial vasculitis is an eruption characterized by inflamed itchy or painful red papules or plaques that resemble urticaria but last longer than 24 hours and heal with residual pigmentation or...
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Influence of Intranasal Drugs on Human Nasal Mucociliary Clearance and Ciliary Beat Frequency

Jiao J, Zhang L

The nasal mucociliary clearance system, which comprises epithelial cilia and mucus from goblet cells, is an important intrinsic defense mechanism of the upper respiratory tract. Intranasal drugs and additives can...
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Drug eruption by antihistamine mistaken for chronic urticaria in a child

Lee GM, Chu SY, Kang SY, Kim HB, Park JS, Kim JK

Although rare, antihistamines can cause adverse effects, including drug-induced eruptions or anaphylaxis. A 4-year-old child visited the pediatric department of a hospital for skin eruptions after administration of antihistamines, (e.g.,...
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Characteristics of poisoning in younger children according to different forms of the drugs

Jang M, Ko Y, Yang HW, Lee J

PURPOSE: This study aimed to investigate the characteristics of poisoning drug ingested by younger children, and to compare the clinical outcome by drug forms. METHODS: This was a retrospective analysis based...
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Urticaria Multiforme with Residual Pigmentation: Two Case Reports

Roh D, Kim WI, Yang MY, Lee WK, Kim TW, Park SM, Lee HJ, Kim GW, Kim HS, Kim BS, Kim MB, Ko HC

  • KMID: 2433642
  • Korean J Dermatol.
  • 2019 Jan;57(1):32-35.
Urticaria multiforme is a cutaneous condition observed in children. This self-limited condition is characterized by well-circumscribed, annular, and erythematous wheals, which spontaneously disappear within a few days. Patients commonly present...
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Updated treatment guideline of chronic spontaneous urticaria

Roh JY

Chronic spontaneous urticaria (CSU), also known as chronic idiopathic urticaria, is a common chronic inflammatory skin disorder that has a prevalence of 0.5% to 1% in the general population. It...
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Development of a Consensus List of Potentially Inappropriate Medications for Korean Older Adults

Kim MY, Etherton-Beer C, Kim CB, Yoon JL, Ga H, Kim HC, Song JS, Kim KI, Won CW

BACKGROUND: Korea has recently attained the aged society status and the growth rate of the aging population will be among the most rapid worldwide. The objective of this study was...
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Age group characteristics of children who visited the emergency department with acute poisoning by ingestion

Ryu WS, Choi JY, Cho JS, Lim YS, Hyun SY, Yang HJ

PURPOSE: To investigate the age group characteristics of children who visited the emergency department with acute poisoning by ingestion. METHODS: We reviewed children under 19 years who visited the emergency department...
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The Efficacy and Safety of Continuous Intravenous Infusion of Low-dose Epinephrine in Patients with Severe Acute Urticaria Who Do Not Achieve Sufficient Responses to Conventional Treatments: An 8-year Retrospective Study

Jeong WS, Hwangbo H, Lee SK

  • KMID: 2436684
  • Korean J Dermatol.
  • 2018 May;56(4):242-250.
BACKGROUND: Acute urticaria sometimes accompanies severe systemic reactions that can be potentially life-threatening. Some patients do not achieve sufficient responses to conventional treatments. There has been no previous study on...
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Intensely Pruritic Papules and Plaques in Waldenstrom's Macroglobulinemia

Lee S, Lee NR, Choe SJ, Kim BJ, Eom M, Choi EH

Waldenstrom's macroglobulinemia (WM) is lymphoplasmacytoid malignancy that affects B lymphocytes. Cutaneous involvement of WM is rare, but various cutaneous manifestations have been reported. These findings are due to various pathological...
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Treatment of Severe Pregnancy Rhinitis Using Microdebrider-Assisted Inferior Turbinoplasty: A Case Report

Shin DB, Lee JO, Chun TU, Lee TH

Pregnancy rhinitis is a relatively common condition. It is characterized by the presence of nasal symptoms, especially nasal congestion, not present prior to pregnancy, but typically present during the last...
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Pathophysiology and new treatment of itch

Jung MJ, Choi YW, Chung BY, Park CW, Kim HO

Many of the patients visit the doctors because of itching sensation. Itching is an unpleasant sensation. In the epidermal keratinocytes, various neurotransmitters and receptors are related itching. The itch signal...
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Epidemiology of Chronic Urticaria in Korea Using the Korean Health Insurance Database, 2010-2014

Lee N, Lee JD, Lee HY, Kang DR, Ye YM

PURPOSE: There are very few epidemiological studies on chronic urticaria (CU). We aimed to investigate the prevalence of CU and to depict demographics and medication patterns for the disease in...
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Factors associated with the treatment of chronic spontaneous urticaria in children

Cho SY, Choi YC, Kim BG, Jung JA

PURPOSE: Chronic spontaneous urticaria (CSU) in children is a common skin disorder, but its clinical course varies. We investigated the clinical course and associated factors for CSU treatment in children. METHODS:...
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Aquagenic Urticaria Diagnosed by the Water Provocation Test and the Results of Histopathologic Examination

Seol JE, Kim DH, Park SH, Kang JN, Sung HS, Kim H

An 18-year-old male visited our department complaining of recurrent episodes of an itchy rash after hand washing, showering/bathing, drinking water, and getting rain-soaked. He was diagnosed with aquagenic urticaria after...
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Pediatric anaphylaxis at a university hospital including the rate of prescribing epinephrine auto-injectors

Gang JS, Kim HS, Bang HH, Kim TH, Lee HJ, Hwangbo Y, Park JS

PURPOSE: Anaphylaxis is an acute, life-threatening systemic reaction which should be treated by epinephrine, and patients should be prescribed epinephrine auto-injector after the event. The purpose of this study was...
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Pathogenesis of allergic conjunctivitis and trends in its treatment

Hwang H

Allergic conjunctivitis is characterized by specific immunologic responses known as type 1 hypersensitivity, resulting in corneal and conjunctival inflammation. Histamine plays an important role in the pathophysiologic mechanism of allergic...
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