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Pathophysiology and new treatment of itch

Jung MJ, Choi YW, Chung BY, Park CW, Kim HO

Many of the patients visit the doctors because of itching sensation. Itching is an unpleasant sensation. In the epidermal keratinocytes, various neurotransmitters and receptors are related itching. The itch signal...
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Pathogenesis of allergic conjunctivitis and trends in its treatment

Hwang H

Allergic conjunctivitis is characterized by specific immunologic responses known as type 1 hypersensitivity, resulting in corneal and conjunctival inflammation. Histamine plays an important role in the pathophysiologic mechanism of allergic...
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Drug hypersensitivity to various antihistamines with cross-reactions

Kim YU, Lee J

Antihistamines (histamine receptor antagonists) are widely prescribed medicines in the treatment of allergic disorders, especially the symptoms of hypersensitivity reactions, mainly blocking the activity of vasoactive amines to their receptors....
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Scombroid Fish Poisoning and Histamine Food Poisoning

Chung SP

Scombroid fish poisoning (SFP) is a form of histamine food poisoning caused by the ingestion of improperly stored fish. The term “scombroid” derives from the family name of the fish...
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Synergistic Effect of H1-Antihistamines on Topical Corticosteroids for Pruritus in Atopic Dermatitis: A Systematic Review and Meta-Analysis

Hur MS, Choe YB, Ahn KJ, Lee YW

BACKGROUND: Although oral antihistamines (H1-histamine receptor antagonists) are the main treatment option for pruritus in general skin dermatosis, their effect in treating pruritus of atopic dermatitis (AD) has not yet...
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Histamine Promotes the Release of Interleukin-6 via the H1R/p38 and NF-kappaB Pathways in Nasal Fibroblasts

Park IH, Um JY, Cho JS, Lee SH, Lee SH, Lee HM

PURPOSE: Based on the close relationship between histamine and interleukin 6 (IL-6), we hypothesized that histamine may regulate the production of cytokines, such as IL-6, during allergic inflammation. Here, we...
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Respiratory Symptoms Relievers: Antitussives, Mucolytics, Antihistamines

Kim SK, Chang J

  • KMID: 2318839
  • Tuberc Respir Dis.
  • 2006 Mar;60(3):261-269.
No abstract available.
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An overview and considerations in prescribing H1-antihistamine

Choi YS, Park YM, Rha YH, Choi SH

H1-antihistamines have been prescribed widely for the treatment of allergic diseases, such as rhinitis, atopic dermatitis, and urticaria besides common colds since the 1940s. H1-antihistamines are classified by chemical structures...
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Contact dermatitis caused by ambulatory blood pressure monitoring

Park BW, Chung JW, Hyon MS, Han DC

No abstract available.
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Efficacy of Stellate Ganglion Block in Cholinergic Urticaria with Acquired Generalized Hypohidrosis

Shin JH, Kim DW, Yang JY, Lee WI

Cholinergic urticaria with acquired generalized hypohidrosis, and its pathophysiology is not well known. Autoimmunity to sweat glands or to acetylcholine receptors on sweat glands has been mentioned as one of...
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A Case of Infantile Acropustulosis Associated with Scabies

Kim KJ, Yi GJ, Ahn KJ

  • KMID: 2303263
  • Korean J Dermatol.
  • 2000 Jul;38(7):985-986.
We report a case of infantile acropustulosis in a 7 month-old female infant who had a family history of scabies in her parents and brother. She had pruritic papulovesicles and...
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A Case of Chronic Cyclitis

Park KB, Yun JH, Choe JK, Ko CJ

  • KMID: 1665774
  • J Korean Ophthalmol Soc.
  • 1980 Sep;21(3):345-349.
Since Ernst Fuchs had described the chronic cyclitis as cyclitis in 1892, there have been many reports about the chronic cyclitis with the development of the binocular indirect ophthalmoscope and...
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Anaphylaxis to Chlorpheniramine Maleate and Literature Review

Choi YW, Jung MJ, Kim HO, Chung BY, Park CW

Chlorpheniramine maleate is commonly used antihistamine. Since antihistamines are the main therapeutic agents for symptomatic treatment of urticaria, anaphylaxis to antihistamines may lead to errors in diagnosis and treatment. We...
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Clinical Pharmacology Review for Primary Health Care Providers: I. Antihistamines

Han S

  • KMID: 2317853
  • Transl Clin Pharmacol.
  • 2014 Jun;22(1):13-18.
Primary health care providers play a critical role in maintaining public health, and the appropriate use of pharmaceutical products is one of the major parts of their practice. This series...
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A Case of Aquagenic Urticaria

Choe SH, Kim YC, Park HJ, Cinn YW

  • KMID: 2303281
  • Korean J Dermatol.
  • 2000 Apr;38(4):512-513.
Aquagenic urticaria is a rare form of physical urticaria. It is manifested as pruritic multiple erythematous maculopapular eruptions mainly on the neck, chest and upper extremities by direct water contact....
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A Case of Recurrent Urticaria Induced by Tartrazine Present in Antihistamine

Hur H

  • KMID: 2303333
  • Korean J Dermatol.
  • 1998 Aug;36(4):742-744.
Antihistamines are commonly used for the treatment of urticaria. Some antihistamines contain dyes and preservatives which have themselves been shown to produce or exacerbate urticaria. Tartrazine is used predominantly as...
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A Case of Solar Urticaria

Whang KH, Kang JS, Koh CJ, Cho CK

  • KMID: 1678256
  • Korean J Dermatol.
  • 1981 Jun;19(3):371-375.
Solar urticaria is a fairly uncommon but Well recognized clinical entity characterized by erythema and wheal with itching immediately following exposure to sunlight or artifical radiation. A 33-year-old female had...
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Bepotastine-induced urticaria, cross-reactive with other antihistamines

Kang JW, Lee J

Second-generation antihistamines are widely prescribed for the control of symptoms of allergic inflammation such as itchy hives, coryza, and itchy eyes. In rare circumstances, these drugs might provoke allergic inflammation....
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Histamine and spontaneously released mast cell granules ffect the cell growth of human hepatocellular carcinoma cells

Lampiasi N, Azzolina A, Montalto G, Cervello M

  • KMID: 1047079
  • Exp Mol Med.
  • 2007 Jun;39(3):284-294.
The role of mast cells in tumor growth is still controversial. In this study we analyzed the effects of both histamine and pre-formed mediators spontaneously released by mast cells on...
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A Case of Papuloerythroderma of Ofuji which Responded to Treatment with Cyclosporine

Jang HC, Kim HJ, Hyun DN, Lee SW, Chung H

  • KMID: 2013937
  • Korean J Dermatol.
  • 2007 Jan;45(1):37-39.
Papuloerythroderma of Ofuji is an uncommon dermatological disorder of unknown etiology and is characterized by a pruritic eruption of widespread confluent papules in vast sheets over the skin, but spares...
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