Korean J Otorhinolaryngol-Head Neck Surg.  2008 Sep;51(9):838-841.

Primary Angiosarcoma of the Parotid Gland

Affiliations
  • 1Department of Otolaryngology, Inje University College of Medicine, Seoul Paik Hospital, Seoul, Korea. cisoo99@yahoo.co.kr
  • 2Department of Pathology, Inje University College of Medicine, Seoul Paik Hospital, Seoul, Korea.

Abstract

Angiosarcoma is an exceedingly rare and highly malignant neoplasm which develops from the endothelium of blood vessels. Only a few cases of primary angiosarcoma of the non-irradiated parotid gland have been reported. In this case, we report a primary angiosarcoma of the parotid gland in a 64-year-old man without prior irradiation of the head and neck region. MRI finding revealed a 3.9x2.7 cm sized mass located in the right parotid gland with unhomogenous enhancement in T2 weighted image. The patient underwent a total parotidectomy and radical neck dissection. The histologic diagnosis was high-grade angiosarcoma showing pleomorphic spindle or epithelioid tumor cells growing as solid infiltrative pattern or slit-like irregular vascular lumina formation. Despite postoperative radiation therapy, the patient died of lung metastasis with hemorrhage 3 months later.

Keyword

Angiosarcoma; Parotid gland; Primary

MeSH Terms

Blood Vessels
Endothelium
Head
Hemangiosarcoma
Hemorrhage
Humans
Lung
Middle Aged
Neck
Neck Dissection
Neoplasm Metastasis
Parotid Gland
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