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A Phase 3 Randomized Clinical Trial to Compare Efficacy and Safety between Combination Therapy and Monotherapy in Elderly Patients with Advanced Gastric Cancer (KCSG ST13-10)

Lee KW, Zang DY, Ryu MH, Han HS, Kim KH, Kim MJ, Koh SA, Lee SS, Koo DH, Ko YH, Sohn BS, Kim JW, Park JH, Nam BH, Choi IS

Purpose This study evaluated whether combination therapy is more effective than monotherapy in elderly patients with metastatic or recurrent gastric cancer (MRGC) as first-line chemotherapy. Materials and Methods Elderly (≥ 70...
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Deviated Nasal Septum and Inferior Turbinate Hypertrophy: Are They the Independent Cause of Sleep-Related Breathing Disorders?

Yun JM, Jo YS, Choi IS

Background and Objectives Nasal obstruction has been assumed to be correlated with sleep-related breathing disorder (SRBD). However, a definite correlation between nasal obstruction and SRBD is still controversial. This study...
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Experimental infection of a porcine kidney cell line with hepatitis A virus

Kim DH, Kim DY, Kim JH, Lim KB, Lee JB, Park SY, Song CS, Lee SW, Choi IS

The hepatitis A virus (HAV) induces severe acute liver injury and is adapted to human and monkey cell lines but not other cells. In this study, the HAV was inoculated...
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Factors Influencing the COVID-19 Vaccination Intentions in Parents for Their Children Aged 5~11: Korea, April 2022

Choi IS, Kim EA

Purpose This study aimed to investigate COVID-19 vaccination intentions in Korean parents for their children aged 5 to 11 years and the factors influencing them. Methods A cross-sectional online survey of 363 parents...
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Salty taste: the paradoxical taste

Choi IS, Kim KN

Taste is a basic sensation to get attracted toward nutritious foods or avoid possible harmful substances. The basic taste qualities in humans consist of sweet, bitter, umami, salty, and sour....
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The results after induction of rabbit anti-thymocyte globulin in the deceased donor kidney transplantation using the grafts of above kidney donor profile index score >65%

Moon JI, Lee SJ, Choi IS

Background: There are limited data concerning the benefits and adverse effects associated with different induction regimens in kidney transplant recipients using the high kidney donor profile index (KDPI) grafts. The...
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Conversion to pancreaticogastrostomy for salvage of disrupted pancreaticojejunostomy following pancreaticoduodenectomy

Lee SJ, Choi IS, Moon JI

Purpose: This study aimed to report on a pancreas-preserving strategy consisting of the conversion to pancreaticogastrostomy (PG) for the salvage of disrupted pancreaticojejunostomy (PJ) following pancreaticoduodenectomy (PD). Methods: This single-center retrospective...
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Optimal indication of single-incision laparoscopic cholecystectomy using Konyang Standard Method in benign gallbladder diseases

Lee SJ, Choi IS, Moon JI, Yoon DS, Choi WJ, Lee SE, Sung NS, Kwon SU, Bae IE, Roh SJ, Kim SG

Purpose: The optimal indications for single-incision laparoscopic cholecystectomy (SILC) have not yet been established. Methods: This single-center retrospective study included consecutive patients who underwent SILC between April 2010 and June 2020....
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The role of postoperative neutrophil-to-lymphocyte ratio as a predictor of postoperative major complications following total gastrectomy for gastric cancer

Kwak JS, Kim SG, Lee SE, Choi WJ, Yoon DS, Choi IS, Moon JI, Sung NS, Kwon SU, Bae IE, Lee SJ, Roh SJ

Purpose: This study was performed to investigate the role of the perioperative neutrophil-to-lymphocyte ratio (NLR) as an early predictor of major postoperative complications after total gastrectomy for gastric cancer. Methods: This...
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Optimal drain management following complicated laparoscopic cholecystectomy for acute cholecystitis: a propensity-matched comparative study

Lee SJ, Choi IS, Moon JI, Yoon DS, Choi WJ, Lee SE, Sung NS, Kwon SU, Bae IE, Roh SJ, Kim SG

Purpose: This study was performed to investigate the effect of drain placement on complicated laparoscopic cholecystectomy (cLC) for acute cholecystitis (AC). Methods: This single-center retrospective study reviewed patients with AC who...
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Is Laparoscopic Common Bile Duct Exploration Safe for the Oldest Old Patients?

Yeon HJ, Moon JI, Lee SJ, Choi IS

Background: This study aimed to identify the risk factors for postoperative complications of laparoscopic common bile duct exploration (LCBDE) in the oldest old patients aged 80 years or older. Methods: From...
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Optimal timing of percutaneous transhepatic gallbladder drainage and subsequent laparoscopic cholecystectomy according to the severity of acute cholecystitis

Lee JS, Lee SJ, Choi IS, Moon JI

Backgrounds/Aims: The optimal timing of percutaneous transhepatic gallbladder drainage (PTGBD) and subsequent laparoscopic cholecystectomy (LC) according to the severity of acute cholecystitis (AC) has not been established yet. Methods: This single-center,...
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Comparison of one-stage laparoscopic common bile duct exploration plus cholecystectomy and two-stage endoscopic sphincterotomy plus laparoscopic cholecystectomy for concomitant gallbladder and common bile duct stones in patients over 80 years old

Lee SJ, Choi IS, Moon JI, Choi YW, Ryu KH

Purpose: This study was performed to compare the safety and efficacy of one-stage laparoscopic common bile duct exploration (LCBDE) plus laparoscopic cholecystectomy (LC) with those of endoscopic sphincterotomy (EST) plus...
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Alterations in the Swallowing Function According to the Severity of Obstructive Sleep Apnea Syndrome

Mun B, Song MK, Yang HC, Choi IS

Objective: Obstructive sleep apnea syndrome (OSAS) is a sleep-related breathing disorder that can have a significant impact on the quality of life. According to recent studies, some OSAS patients exhibit...
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Effect of omalizumab as add-on therapy to Quality of Life Questionnaire for Korean Asthmatics (KAQLQ) in Korean patients with severe persistent allergic asthma

Jung JW, Park HS, Park CS, Cho SH, Choi IS, Moon HB, Kwon SS, Yoon HJ, Park JW, Lee JM, Choi DC, Choi BW

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Assessment of the Test-Retest Reliability of Level III Polysomnography: Comparison of Results Using Difference of Apnea-Hypopnea Index Score and Severity of Obstructive Sleep Apnea

Han BH, Yun JM, Choi IS

Background and Objectives Although studies of test-retest reliability of the standard polysomnography has been reported numerous times, studies of portable sleep devices have been reported in very few cases to...
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Effect of omalizumab as add-on therapy to Quality of Life Questionnaire for Korean Asthmatics (KAQLQ) in Korean patients with severe persistent allergic asthma

Jung JW, Park HS, Park CS, Cho SH, Choi IS, Moon HB, Kwon SS, Yoon HJ, Park JW, Lee JM, Choi DC, Choi BW

Background/Aims: Omalizumab is the first biologic known to be effective in patients with severe allergic asthma. Methods: This study was conducted as a multicenter, single-group, open trial to evaluate the improvement...
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Efficacy of sentinel lymph node biopsy with radioisotope alone and the prediction of sentinel node status using PET-CT in breast cancer

Song R, Kwon SU, Yoon DS, Bae IE, Choi IS, Choi WJ, Lee SE, Moon JI, Sung NS, Lee SJ, Roh SJ, Kim SG

Purpose: Sentinel lymph node biopsy (SLNB) using both a radioactive isotope (RI) and blue dye is considered highly effective; however, there were limitations with the use of both agents in...
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Implantable cardioverter defibrillator as a treatment for massive left ventricular fibroma-induced ventricular arrhythmia in a child

Choi IS, Jeong HK, Park HW, Kim YS

Pediatric cardiac tumors are rare. Among these, cardiac fibroma is the second most common. Its clinical manifestations depend on size and location of the tumor and include arrhythmia or obstruction...
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Melanotic Oncocytic Metaplasia of the Nasopharynx in the Patient with Suspicious Hemoptysis: Case Report

Cheong TY, Kim HS, Choi IS

Melanotic oncocytic metaplasia (MOM) in the nasopharyngeal space is a very rare entity. Only 35 cases have been reported in the English literature, and most patients were East Asian males...
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