Korean J Otolaryngol-Head Neck Surg.  2004 Mar;47(3):263-267.

Usefulness of 99mTc-MIBI SPECT and CT in the Evaluation of Cervical Lymph Node Metastasis

Affiliations
  • 1Department of Otolaryngology, College of Medicine, Pusan National University, Busan, Korea. wangsg@pusan.ac.kr
  • 2Department of Nuclear Medicine, College of Medicine, Pusan National University, Busan, Korea.
  • 3Department of Diagnostic Radiology, College of Medicine, Pusan National University, Busan, Korea.

Abstract

BACKGROUND AND OBJECTIVES
The aim of this study was to compare the effectivenss of 99mTc-MIBI SPECT and CT in evaluating cervical lymph node (LN) metastasis of head and neck cancer. MATERIALS AND METHOD: Histopathologic results of 138 cervical lymph node levels in 26 neck dissected patients were compared with preoperative CT and 99mTc-MIBI SPECT findings about cervical lymph node metastasis. RESULTS: Sensitivity, specificity and predictability of CT and 99mTc-MIBI SPECT were 63.2, 91.6, 87.7% and 52.6, 84.9, 80.4%, respectively. When analyzing CT and 99mTc-MIBI SPECT together, sensitivity and specificity was 78.9, 99.2%, respectively. CONCLUSION: The combined use of 99mTc-MIBI SPECT and CT could increase the accuracy, compared with the single use of either 99mTc-MIBI SPECT or CT, to detect cervical LN metastases.

Keyword

Tc-MIBI; Computed tomography; Head and neck cancer

MeSH Terms

Head and Neck Neoplasms
Humans
Lymph Nodes*
Neck
Neoplasm Metastasis*
Sensitivity and Specificity
Tomography, Emission-Computed, Single-Photon*
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