Korean J Pathol.
2003 Oct;37(5):362-364.
Dedifferentiated Liposarcoma with a Peculiar Whorling Pattern: A Case Report
- Affiliations
-
- 1Department of Pathology, Seonam Univerisy College of Medicine, Namwon, Korea. jshinlee@hanmail.net
- 2Department of General Surgery, Seonam Univerisy College of Medicine, Namwon, Korea.
Abstract
- A dedifferentiated liposarcoma is a uncommon neoplasm characterized by the coexistence of a well-differentiated liposarcoma and non-lipogenic sarcomas. A peculiar neural-like or meningothelial-like whorling pattern of dedifferentiation has recently been reported. We report a case of dedifferentiated liposarcoma with a peculiar whorling pattern in the scrotum of a 76-year-old man. Histologically, the tumor consisted of areas of a well differentiated liposarcoma admixed with areas of a morphologically non-lipogenic sarcoma. The whorls were scattered throughout the tumor. The cells in the whorls and dedifferentiated area showed a significant nuclear PCNA and p53 protein reactivity.
