Korean J Med.  2014 Jul;87(1):67-71.

Cushing's Syndrome Caused by an ACTH-Producing Neuroendocrine Carcinoma of the Gallbladder

Affiliations
  • 1Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. mhkim@amc.seoul.kr
  • 2Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Abstract

Neuroendocrine tumors of the gallbladder are rare, and typically found incidentally after a cholecystectomy. Few data are available on adrenocorticotrophic hormone (ACTH)-producing neuroendocrine tumors originating specifically from the gallbladder. We experienced the case of a patient with a gallbladder mass who presented with Cushing's syndrome, who was subsequently diagnosed as an ACTH-producing neuroendocrine carcinoma of the gallbladder. Despite being rare, hormone-producing neuroendocrine tumors should be part of the differential diagnosis in patients with Cushing's syndrome.

Keyword

Gallbladder neuroendocrine carcinoma; Cushing's syndrome; Ectopic ACTH syndrome

MeSH Terms

ACTH Syndrome, Ectopic
Adrenocorticotropic Hormone
Carcinoma, Neuroendocrine*
Cholecystectomy
Cushing Syndrome*
Diagnosis, Differential
Gallbladder*
Humans
Neuroendocrine Tumors
Adrenocorticotropic Hormone
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