Korean J Med.  2016 Feb;90(2):148-153. 10.3904/kjm.2016.90.2.148.

Staphylococcus-associated Glomerulonephritis

Affiliations
  • 1Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. sbkim@amc.seoul.kr
  • 2Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Abstract

A 64-year-old woman was admitted with vertebral osteomyelitis and polyarthritis (both knees and the right shoulder). She had had no health problems before these conditions developed. Joint culture grew methicillin-resistant Staphylococcus aureus. During hospitalization, hematuria, proteinuria, azotemia, and decreased C3 were reported. The renal biopsy showed mesangial proliferative glomerulonephritis with C3 and IgA co-dominant deposits on immunofluorescence staining. Following incision and drainage of the right shoulder and right knee, and intravenous vancomycin for 15 weeks, the C-reactive protein, proteinuria, hematuria, and C3 level all normalized. Here, we report a case of Staphylococcus-associated glomerulonephritis with a brief review of the literature.

Keyword

Glomerulonephritis; Methicillin-Resistant Staphylococcus aureus

MeSH Terms

Arthritis
Azotemia
Biopsy
C-Reactive Protein
Drainage
Female
Fluorescent Antibody Technique
Glomerulonephritis*
Hematuria
Hospitalization
Humans
Immunoglobulin A
Joints
Knee
Methicillin-Resistant Staphylococcus aureus
Middle Aged
Osteomyelitis
Proteinuria
Shoulder
Vancomycin
C-Reactive Protein
Immunoglobulin A
Vancomycin
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