Ann Dermatol.  2013 Feb;25(1):88-91. 10.5021/ad.2013.25.1.88.

Extramammary Paget's Disease of External Genitalia with Bowenoid Features

Affiliations
  • 1Department of Dermatology, Dankook University Medical College, Cheonan, Korea. ivymyung@dankook.ac.kr

Abstract

Extramammary Paget's disease (EMPD) is an uncommon intraepithelial adenocarcinoma, primarily affecting the apocrine-bearing skin. Bowen disease is an intraepithelial squamous cell carcinoma having the potential to become invasive carcinoma. The histopathological concomitant features between EMPD and Bowen disease have been described. One theory is that primary EMPD arises multicentrically, within the epidermis from the pluripotent stem cells. Herein, we describe a case of EMPD that had bowenoid features, and review the previous cases associated with the origin of EMPD.

Keyword

Bowen's disease; Extramammary Paget's disease; Male genitalia

MeSH Terms

Adenocarcinoma
Bowen's Disease
Carcinoma, Squamous Cell
Epidermis
Genitalia
Genitalia, Male
Male
Paget Disease, Extramammary
Pluripotent Stem Cells
Skin
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