Ann Dermatol.  2013 Aug;25(3):385-386. 10.5021/ad.2013.25.3.385.

Primary Dermal Melanoma Latent for More than 10 Years

• Moriue J
• Yoneda K
• Moriue T
• Nakai K
• Katsuki N
• Haba R
• Ikeda M
• Kubota Y

• KMID: 2265888
• DOI: http://doi.org/10.5021/ad.2013.25.3.385

Abstract

No abstract available.

MeSH Terms

Melanoma

Figure

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  Fig. 1 (A) Brown/red nodule on the sacral region. (B) Primary dermal melanoma composed of a dermal and subcutaneous nodule surrounded by fibrous tissue, with extensive central necrosis and hemorrhaging (H&E, ×10).

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  Fig. 2 Immunohistochemical findings of primary dermal melanoma. (A) HMB-45 staining was focally positive (×200). (B) Ki-67 staining was low positive (14.9% of cells were positive) (×200).

Reference

1. Bowen GM, Chang AE, Lowe L, Hamilton T, Patel R, Johnson TM. Solitary melanoma confined to the dermal and/or subcutaneous tissue: evidence for revisiting the staging classification. Arch Dermatol. 2000; 136:1397–1399.

2. Cassarino DS, Cabral ES, Kartha RV, Swetter SM. Primary dermal melanoma: distinct immunohistochemical findings and clinical outcome compared with nodular and metastatic melanoma. Arch Dermatol. 2008; 144:49–56.

3. Balch CM, Gershenwald JE, Soong SJ, Thompson JF, Atkins MB, Byrd DR, et al. Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol. 2009; 27:6199–6206.

4. Hida Y, Kubo Y, Miyajima O, Arase S. Primary dermal melanoma: a case report and molecular characterization. J Dermatol. 2009; 36:346–352.