Ann Dermatol.  2012 Aug;24(3):373-375. 10.5021/ad.2012.24.3.373.

Topical Diphencyprone as an Effective Treatment for Cutaneous Metastatic Melanoma

• Kim YJ

• KMID: 2265319
• DOI: http://doi.org/10.5021/ad.2012.24.3.373

Abstract

No abstract available.

MeSH Terms

Cyclopropanes
Melanoma
Cyclopropanes

Figure

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  Fig. 1 Multiple erythematous superficial and deep nodules on right shin before the diphencyprone treatment.

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  Fig. 2 Moderate dry eczematous changes with no evidence of nodules after 18 weeks of weekly diphencyprone application.

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  Fig. 3 Infiltrate of dermis by neoplastic cells with prominent nucleoli (A: H&E, ×100), staining with HMB 45 (B: ×100), consistent with metastatic melanoma, before the diphencyprone treatment.

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  Fig. 4 Marked spongiosis with numerous eosinophils, consistent with allergic contact dermatitis, but no evidence of melanoma, after the diphencyprone treatment, on low-power view (A: H&E, ×100) and high-power view (B: H&E, ×200).

Reference

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