Korean J Med.
2012 Dec;83(6):823-827.
Platelet Dysfunction in a Patient with Multiple Myeloma: A Case Report with a Literature Review
- Affiliations
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- 1Department of Internal Medicine, Asan Medical Center, University of Ulsan Collage of Medicine, Seoul, Korea. csuh@amc.seoul.kr
- 2Department of Laboratory Medicine, Asan Medical Center, University of Ulsan Collage of Medicine, Seoul, Korea.
Abstract
- Multiple myeloma is a monoclonal plasma cell proliferation disorder with various symptoms and signs caused by paraproteinemias. Among these signs, a bleeding tendency is one of the major fatal causes. However, significant severe bleeding is rare in most cases. In this study, we report a case of multiple myeloma in a patient who had a severe recurrent bleeding tendency due to platelet dysfunction caused by paraproteins. After being treated with therapeutic plasma exchange and chemotherapy, the patient's monoclonal protein level decreased and the bleeding stopped.
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