Korean J Med.  2012 Mar;82(3):378-381.

A Case of Mycobacterium Marinum Tenosynovitis Diagnosed by the PCR-restriction Fragment Length Polymorphism of the rpoB Gene

Affiliations
  • 1Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. drchung@skku.edu

Abstract

Mycobacterium marinum is an uncommon cause of skin and soft-tissue infection. The diagnosis of M. marinum infection is often delayed when only a conventional tissue culture method is used. PCR-restriction fragment length polymorphism (RFLP) analysis using the novel region of the rpoB gene is now available for the rapid identification of Mycobacteria. We report a case of hand infection caused by M. marinum that was identified by PCR-RFLP analysis. The PCR-RFLP assay is a specific and rapid method for the identification of Mycobacteria that facilitates the early diagnosis of non-tuberculous Mycobacterium infection.

Keyword

Mycobacterium marinum; PCR-restriction fragment length polymorphism (RFLP) analysis; rpoB gene

MeSH Terms

Early Diagnosis
Hand
Mycobacterium
Mycobacterium Infections
Mycobacterium marinum
Skin
Tenosynovitis
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