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Protocol of a Nationwide Observational Study among Patients with Nontuberculous Mycobacterium Pulmonary Disease in South Korea (NTM-KOREA)

Kwak N, Choi H, Jeon D, Jhun BW, Jo KW, Kang YA, Kwon YS, Lee M, Mok J, Shim TS, Shin HJ, Whang J, Yim JJ

BACKGROUND: The burden of nontuberculous mycobacterial (NTM) pulmonary disease (PD) is increasing globally. To understand the treatment outcomes and prognosis of NTM-PD, a unified registry is needed. In this project,...
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Frequency of Mycobacterium tuberculosis Among M. tuberculosis Complex Strains Isolated from Clinical Specimen

Cho H, Kim JB, Uh Y

BACKGROUND: Rapid and accurate detection of Mycobacterium tuberculosis (MTB) is of primary importance for infection control and selection of anti-tuberculosis drugs. However, most clinical laboratories report MTB complex (MTC) without...
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Treatment Outcomes after Discontinuation of Ethambutol due to Adverse Events in Mycobacterium avium Complex Lung Disease

Kwon YS, Kwon BS, Kim OH, Park YE, Shim TS, Chong YP, Jo KW

BACKGROUND: Long-term administration of ethambutol (EMB) for Mycobacterium avium complex lung disease (MAC-LD) sometimes leads to permanent discontinuation of EMB due to various adverse events. This study aimed to investigate...
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Peritoneal Dialysis Catheter-Related Infection due to Mycobacterium abscessus Confused with Rhodococcus

Jung JH, Ahn SH

No abstract available.
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First Report of Tenosynovitis Caused by Mycobacterium virginiense in Korea

Oh S, Lee KH, Heo ST, Kim GM, Kim YR, Yoo JR

No abstract available.
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Diagnostic Performance of the GENEDIA MTB/NTM Detection Kit for Detecting Mycobacterium tuberculosis and Nontuberculous Mycobacteria With Sputum Specimens

Shin S, Yoo IY, Shim HJ, Kang OK, Jhun BW, Koh WJ, Huh HJ, Lee NY

The GENEDIA MTB/NTM Detection Kit (GENEDIA MTB/NTM; Green Cross Medical Science Corp., Chungbuk, Korea) is a multiplex real-time PCR assay used for differential identification of Mycobacterium tuberculosis complex (MTBC) and...
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Evaluation of the QuantaMatrix Multiplexed Assay Platform for Molecular Diagnosis of Multidrug- and Extensively Drug-Resistant Tuberculosis Using Clinical Strains Isolated in Myanmar

Chang Y, Kim S, Kim Y, Ei PW, Hwang D, Lee J, Chang CL, Lee H

BACKGROUND: Although the incidence of tuberculosis (TB) is decreasing, cases of multidrug-resistant (MDR) TB and extensively drug-resistant (XDR) TB continue to increase. As conventional phenotype drug susceptibility testing (pDST) takes...
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Different Quantitative Interferon-γ Response in Active Tuberculosis of Various Primary Infection Sites

Lee H, Kim KH

BACKGROUND: The quantitative interferon (IFN)-γ response in the IFN-γ release assay (IGRA) has been investigated to predict progression from Mycobacterium tuberculosis infection to active tuberculosis (TB). However, the significance of...
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Effectiveness of Intravenous Isoniazid and Ethambutol Administration in Patients with Tuberculosis Meningoencephalitis and HIV Infection

Butov D, Feshchenko Y, Kuzhko M, Gumenuik M, Yurko K, Grygorova , Tkachenko , Nekrasova , Tlustova T, Kikinchuk , Peshenko A, Butova T

BACKGROUND: The aim of this study was to investigate the effectiveness of intravenous isoniazid (H) and ethambutol (E) administered in patients with new sputum positive drug-susceptible pulmonary tuberculosis (TB) with...
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Public Health Center on Tuberculosis Management in Korea: From 1945 to the Late 1970s

Kwon OY

Tuberculosis (TB) was called “ruinous disease” in colonial Korea. However, it is no longer a threat to the lives of the Korean people. Public Health Centers (PHC) have played a...
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Calcaneal Osteomyelitis Presenting as a Paradoxical Reaction during Treatment of Multidrug-Resistant Tuberculosis

Han YH, Lee CH, Bae MJ, Hwang K

Tuberculosis in the foot progresses gradually; thus, diagnosis is usually delayed, and early treatment is rarely provided. If osteomyelitis occurs due to delayed diagnosis and treatment, surgical treatment should be...
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Relapsed Leprosy with Multiple Ulcerative Skin Lesions: A Case Report

Jeong HH, Hong SG, Park JM, Kim JP, Heo EP, Go JW

Leprosy is a chronic infectious and granulomatous disease caused by Mycobacterium leprae. It is treated with a multidrug therapy (MDT), which is consisted of dapsone, rifampicin, and clofazimine. However, there...
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Effect of temperature and medium on the viability of Mycobacterium leprae during long term-storage

Park JH, Kim YJ, Kim JP

BACKGROUND: Mycobacterium leprae (M. leprae) is pathogenic bacterium with polymorphic, acid-fast properties and causes leprosy that it is called Hansen's disease. Leprosy can be completely cured using multidrug therapy (MDT),...
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Comparison of Effective DNA Extraction method for Molecular biological study of Mycobacterium leprae

Kim YJ, Park JH, Kim JP

BACKGROUND: Leprosy is an important health problem in many geographical areas yet. It is caused through a cough or contact with fluid from the nose of a person infected by...
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Cluster of Lymphadenitis due to Nontuberculous Mycobacterium in Children and Adolescents 8–15 Years of Age

Park SG, Kim H, Paik JH, Park KU, Park JS, Jeong WJ, Jung YH, Na JI, Sung KH, Kim JY, Lee H, Lee H

BACKGROUND: Nontuberculous mycobacteria (NTM) lymphadenitis is an under-recognized entity, and data of the true burden in children are limited. Without a high index of suspicion, diagnosis may be delayed and...
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A Case of Cutaneous Mycobacterium chelonae Infection Induced by Body Scurbbing

Shin JY, Eun DH, Lee JY, Yoon TY

No abstract available.
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First Isolation of Mycobacterium virginiense From a Human Pulmonary Specimen

Jung J, Yoo IY, Jhun BW, Koh WJ, Lee NY, Huh HJ

No abstract available.
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Inflammatory Myofibroblastic Tumor of the Retroperitoneum Including Chronic Granulomatous Inflammation Suggesting Tuberculosis: A Case Report

Kim Y, Park JW, Kim S, Lee KY, Bae J, Jeon YK, Im JM, Ryoo SB, Jeong SY, Park KJ

An inflammatory myofibroblastic tumor (IMT) is a solid tumor of unknown etiology frequently affecting children and young adults and commonly affecting the lung or orbital region. We present a case...
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microRNAs in Mycobacterial Infection: Modulation of Host Immune Response and Apoptotic Pathways

Agarwal RG, Sharma P, Nyati KK

Our current knowledge of mycobacterial infections in humans has progressively increased over the past few decades. The infection of Mycobacterium tuberculosis causes tuberculosis (TB) disease, which has reasoned for excessive...
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Good Agreement between an Interferon Gamma Release Assay and Tuberculin Skin Tests in Testing for Latent Tuberculosis Infection among HIV-Infected Patients in Indonesia

Reviono R, Saptawati , Redhono D, Suryawati

BACKGROUND: Latent tuberculosis infection is a condition where there is a persistent immune response to Mycobacterium tuberculosis without clinical manifestations of tuberculosis. Currently, there is no gold standard to diagnose...
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