Korean J Med.  2010 May;78(5):660-663.

A case of anaphylaxis to erythromycin

Affiliations
  • 1Department of Internal Medicine, Medical Research Institute, Chungbuk National University College of Medicine, Chungbuk, Korea. kimmk@chungbuk.ac.kr
  • 2Regional Drug Vigilence Center, Chungbuk National University College of Medicine, Chungbuk, Korea.

Abstract

Macrolides antibiotics synthesized by Streptomyces strains are prescribed widely and seldom produce hypersensitivity reactions, even when administered topically. Consequently, they are considered very safe drugs. We report the case of a 32.year.old woman who developed anaphylactic shock after ingesting erythromycin, which she had taken twice before. The previous exposure to erythromycin, clinical findings, and a positive skin intradermal test with erythromycin (10 mg/mL) support the postulate that anaphylaxis was induced by erythromycin.

Keyword

Erythromycin; Anaphylaxis; Skin test

MeSH Terms

Anaphylaxis
Anti-Bacterial Agents
Erythromycin
Female
Humans
Hypersensitivity
Intradermal Tests
Macrolides
Skin
Skin Tests
Streptomyces
Anti-Bacterial Agents
Erythromycin
Macrolides
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