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Current practice of antibiotics skin test in pediatric inpatients: A single-center experience

Roh YY, Kim H, Park M, Kim SY, Kim JD, Kim MJ, Lee YJ, Kim YH, Kim KW, Sohn MH

Background: Routine practice of antibiotic skin test (AST) before administering antibiotics is with little scientific basis. However, AST is frequently performed in real-world practice. We aimed to explore the current...
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Interferon-gamma release assay has poor diagnostic accuracy in differentiating intestinal tuberculosis from Crohn’s disease in tuberculosis endemic areas

Sachdeva K, Kumar P, Kante B, Vuyyuru SK, Mohta S, Ranjan MK, Singh MK, Verma M, Makharia G, Kedia S, Ahuja V

Background/Aims: Intestinal tuberculosis (ITB) and Crohn’s disease (CD) frequently present with a diagnostic dilemma because of similar presentation. Interferon-gamma release assay (IGRA) has been used in differentiating ITB from CD,...
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Hypersensitivity Reactions to Anticancer Monoclonal Antibodies

Choi B, Jang HY, Kang HR, Oh JM

Therapeutic monoclonal antibodies (TmAbs) are new treatment options for cancer. While their use is more common, hypersensitivity reactions (HSRs) to these drugs have been increased, preventing the use of first-line therapies....
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Management of hypersensitivity reactions to contrast media

Seo JH, Jeong J, Yun JE, Lee SY, Kang HR

As imaging technologies have become essential for diagnosing various diseases, the use of contrast agents is rapidly expanding. As a result, hypersensitivity reactions (HSRs) to contrast agents have also increased....
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Change in sensitization to inhalant allergens in adults with respiratory allergic disease in Busan and Gyeongsangnam-do province

Park CS, Jo EJ, Kim M, Nam YH, Lee SE, Choi GS, Jeong YY, Kim HK, Oh JW, Park HK

Purpose: It is crucial to identify the causative allergen of respiratory allergic disease. Air pollution and climate change affect the allergen concentration as well as the sensitization rate. This study...
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Expert opinion: The clinical usefulness of skin tests prior to the administration of beta-lactam antibiotics

Kim SR, Kim S, Kim SH, Park JS, Park HJ, Suh DI, Sim DW, Yang MS, Lee JH, Lee HY, Jung JW, Choi M, Kang HR, Drug Allergy Working Group of Korean Academy of Asthma Allergy and Clinical Immunology

An allergy skin test is used to diagnose certain allergies by identifying sensitized allergens. In other words, it is a test for patients who are already sensitized to certain allergens....
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Recent Updates on Diagnosis and Prevention of Hypersensitivity Reactions to Iodinated Contrast Media

Kim S

Iodinated contrast media (ICM) have become one of the major causes of drug hypersensitivity reactions with the increase in ICM-based radiological imaging. The strategies for diagnosing and preventing ICM-induced hypersensitivity...
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Current practice for diagnosing immediate drug hypersensitivity reactions in Korea

Kang SY, Yang MS, Song WJ, Cho SH

Background/Aims: Skin (STs) and drug provocation (DPTs) tests are essential for identifying the culprit drugs causing drug hypersensitivity reactions (DHRs). Several protocols have been developed for the identification of some...
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Beta-Lactam Allergy: Real Practice in a Regional Hospital

Kim H, Lee J, Kim S

Background/Aims: Beta-lactam (BL) antibiotics are widely prescribed for controlling bacterial infections and relevant culprits of adverse drug reactions (ADRs). BL allergy may vary according to prescription patterns within a given...
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Cluster Analysis of Inhalant Allergens in South Korea: A Computational Model of Allergic Sensitization

Kim DK, Park YS, Cha KJ, Jang D, Ryu S, Kim KR, Kim SH, Yoon HJ, Cho SH

Objectives. Sensitization to specific inhalant allergens is a major risk factor for the development of atopic diseases, which impose a major socioeconomic burden and significantly diminish quality of life. However,...
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The Relation of Autologous Serum Skin Test andAutologous Plasma Skin Test Result with VariousClinical and Laboratory Findings in Patients withChronic Spontaneous Urticaria

Park GH, Choi JH, Kim S, Bae Y

Background: Despite the autologous serum skin test (ASST)and autologous plasma skin test (APST) is widely used test accessingwhether a patient with chronic spontaneous urticaria(CSU) has autoreactivity or not, the clinician...
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Anaphylaxis induced by sugammadex and sugammadex-rocuronium complex -a case report-

Choi SC, Han S, Kwak J, Lee JY

Background: In sugammadex-induced anaphylaxis, sugammadex and/or sugammadex-rocuronium complex have possible allergenic epitope. Case: We report a case of sugammadex-induced anaphylaxis during general anesthesia in a 60-year-old male undergoing...
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Recent updates of iodinated contrast media hypersensitivity

Cho MK, Lee SY, Kang HR

Previously, immediate reactions to ionic high-osmolar iodinated contrast media (ICM) were regarded as nonimmunological. However, despite the use of lower-osmolar ICM, ICM hypersensitivity still occurs in some patients and recent...
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Prevalence and Risk Factors of Latent Tuberculosis Infection among Healthcare Workers Using Tuberculin Skin Test and Interferon-γ Release Assay at a Tertiary Hospital in South Korea

Kim SJ, Ha E, Park ES, Choi JY, Kang YA

Background: We evaluated the prevalence and risk factors associated with latent tuberculosis infections (LTBIs) among healthcare workers (HCWs) working in non-TB departments in a tertiary referral hospital. Methods: This study was...
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Prescreening skin test effectiveness in predicting hypersensitivity to iodinated contrast media

Kim TB

Hypersensitivity reaction to iodinated contrast media (ICM) is a persistent clinical issue owing to widespread use of computed tomography (CT) examinations. The question of whether routine performance of skin tests...
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Results of Intradermal Skin Testing with Cefazolin according to a History of Hypersensitivity to Antibiotics

Kwon JW, Kim YJ, Yang MS, Song WJ, Kim SH, Cho SH, Chang YS

BACKGROUND: The relationship between cephalosporin hypersensitivity and a history of β-lactam hypersensitivity is unclear. We evaluated the usefulness of routine intradermal cefazolin skin testing and its relationship with the history...
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Optimization of Allergen Panels for Diagnosis of Allergic Rhinitis

Lee J, Kim JK, Kim KS, Rhee CS

The selection of allergen panel is very important to test for innumerable allergens throughout the Korea. However, the allergens studied are heterogeneous depending on the area the patient live and...
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IgE-mediated allergy to proton pump inhibitors with both delayed and immediate onset

Barakat L, Vasconcelos MJ, Bourrain J, Demoly P, Chiriac AM

Proton pump inhibitors (PPIs) are widely used for the treatment of gastrointestinal diseases. Incidence of drug hypersensitivity reactions (DHRs) to PPIs has been rising, presumably because of their increased consumption....
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Good Agreement between an Interferon Gamma Release Assay and Tuberculin Skin Tests in Testing for Latent Tuberculosis Infection among HIV-Infected Patients in Indonesia

Reviono R, Saptawati , Redhono D, Suryawati

BACKGROUND: Latent tuberculosis infection is a condition where there is a persistent immune response to Mycobacterium tuberculosis without clinical manifestations of tuberculosis. Currently, there is no gold standard to diagnose...
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Diagnosis and treatment of latent tuberculosis infection

Min J, Kim JS

In order to eliminate tuberculosis worldwide by 2050, effective management of latent tuberculosis infection is essential, and policy-makers have begun to recognize the importance of scaling up preventive therapy. The...
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