Korean J Med.
2009 Nov;77(5):610-615.
A case of undifferentiated carcinoma with osteoclast-like giant cells of the pancreas
- Affiliations
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- 1Department of Internal Medicine, Gil Medical Center, Gachon University of Medicine and Science, Incheon, Korea. yskoo@gilhospital.com
- 2Department of General Surgery, Gil Medical Center, Gachon University of Medicine and Science, Incheon, Korea.
- 3Department of Pathology, Gil Medical Center, Gachon University of Medicine and Science, Incheon, Korea.
Abstract
- An osteoclast-like giant cell tumor of the pancreas is a very rare neoplasm, with only three cases reported in Korea. Due to the rarity of this tumor type, few clinical data are available. We present a case of undifferentiated carcinoma with osteoclast-like giant cell tumor arising in the tail of the pancreas in a 72-year-old woman hospitalized to evaluate epigastric pain and a palpable abdominal mass. Magnetic resonance imaging revealed the presence of a large enhancing mass with septation arising from the tail of the pancreas. A distal pancreatectomy with splenectomy was performed. The pathological diagnosis was undifferentiated carcinoma with osteoclast-like giant cell tumor. Here, we describe the histopathological and immunohistochemical findings and review the clinical features of the cases reported in the Korean literature.
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