Korean J Med.
2008 Aug;75(2):230-236.
Four cases of chloroma treated with hematopoietic stem cell transplantation
- Affiliations
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- 1Catholic Hemopoietic Stem Cell Transplantation Center, Seoul, Korea. cumckim@catholic.ac.kr
- 2Department of Internal Medicine, St. Mary's Hospital, Seoul, Korea.
- 3Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea.
Abstract
- Chloroma is an invasive extramedullary tumor composed of immature myeloid cells, which complicates the clinical course in a minority of patients with acute myeloid leukemia (AML). The presence of myeloid sarcoma is known to be a poor prognostic indicator in patients with AML. However, the optimal treatment of AML with concurrent chloroma has not been determined. We report four patients with AML accompanied by concurrent chloroma from the time of initial diagnosis. All of the patients underwent hematopoietic stem cell transplantation after complete remission. We also present a review of the literature.
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