Korean J Nephrol.  2000 May;19(3):558-562.

A Case of Chronic Inflammatory Demyelinating Polyneuropathy in Lupas Nephritis

Affiliations
  • 1Department of Internal Medicine, Sungkuynkwan University School of Medicine, Kangbuk Samsung Hospital, Korea.
  • 2Department of Neurology, Sungkuynkwan University School of Medicine, Kangbuk Samsung Hospital, Korea.
  • 3Department of Pathology, Sungkuynkwan University School of Medicine, Kangbuk Samsung Hospital, Korea.
  • 4Department of Pathology, College of Medicine, Hanyang University, Korea.
  • 5Department of Internal Medicine, College of Medicine, Pochon CHA University, Seoul Korea.

Abstract

Systemic lupus erythematosus(SLE) is a multisys-temic disease. Peripheral neuropathy occurs in about 10% of patients with SLE. Chronic inflammatory demyelinating polyneurpathy has been reported rarely in SLE. We experienced a case of chronic inflammatory polyneuropathy in lupus nephritis. 32-year-old housewife presented to chronic progressive muscle weakness and heavy proteinuria. Kidney biopsy showed compatible with lupus nephritis (WHO Class V, membranous nephropathy). Nerve conduction studies showed reduction in conduction velocity and sural nerve biopsy revealed demyeli-nating polyneuropathy. Steroid therapy led to improvement in clinical symptoms and proteinuria.

Keyword

Systemic lupus erithematosus; Chro-nic inflammatory demyelinating poly-neuropathy; Sural nerve biopsy

MeSH Terms

Adult
Biopsy
Humans
Kidney
Lupus Nephritis
Muscle Weakness
Nephritis*
Neural Conduction
Peripheral Nervous System Diseases
Polyneuropathies*
Proteinuria
Sural Nerve
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