Korean J Nephrol.  1997 Dec;16(4):778-782.

A Case of Bartter-like Syndrome in a Patient of Drug-induced Interstitial Nephritis Associated with Rheumatoid Arthritis

Affiliations
  • 1Department of Internal Medicine, Pusan National University Hospital, Pusan, Korea.

Abstract

A 59-year-old female patient with rheumatoid arthritis showed hypokalemic metabolic alkalosis, normotensive hyperreninemic hyperaldosteronism and high urinary prostaglandin level. She was thought to have Bartter's syndrome. But, her kidney biopsy specimen showed chronic interstitial nephritis. She have used acetaminophen containing analgesics for recent three years. So we thought her disease was caused by drug. But, in this case, clinical manifestations are correspond with Bartter's syndrome and we have witnessed a successful respond to kalium replacement, angiotensin converting enzyme inhibitor, prostaglandin inhibitor and spironolactone administration.

Keyword

Bartter-like syndrome; Drug-induced interstitial nephritis

MeSH Terms

Acetaminophen
Alkalosis
Analgesics
Arthritis, Rheumatoid*
Bartter Syndrome
Biopsy
Female
Glycogen Storage Disease Type VI
Humans
Hyperaldosteronism
Kidney
Middle Aged
Nephritis, Interstitial*
Peptidyl-Dipeptidase A
Prostaglandin Antagonists
Spironolactone
Acetaminophen
Analgesics
Peptidyl-Dipeptidase A
Prostaglandin Antagonists
Spironolactone
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