Korean J Med.  2005 Apr;68(4):463-466.

Primary Sjogren's syndrome presenting as acute transverse myelitis

Affiliations
  • 1Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea. ysong@snu.ac.kr

Abstract

Sjogren's syndrome is one of chronic inflammatory autoimmune diseases involving exocrine gland. Involvement of central nerve system was rarely reported. We report a case of primary Sjogren's syndrome presenting as transverse myelitis in 37-year-old female who complained of tingling sense in both legs and voiding difficulty. Magnetic resonance imaging shows high signal intensity with cord swelling from C6 to T7 in T2 weighted image. The patient received intravenous methylprednisolone (1,000 mg/day) for 10 days followed by prednisolone and intravenous monthly cyclophosphamide with subsequent clinical improvement.

Keyword

Sjogren's syndrome; Transverse myelitis; Corticosteroid; Cyclophosphamide

MeSH Terms

Adult
Autoimmune Diseases
Cyclophosphamide
Exocrine Glands
Female
Humans
Leg
Magnetic Resonance Imaging
Methylprednisolone
Myelitis, Transverse*
Prednisolone
Sjogren's Syndrome*
Cyclophosphamide
Methylprednisolone
Prednisolone
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