Korean J Nephrol.  2010 Jul;29(4):525-528.

Kaposi's Sarcoma in a Patient on Hemodialysis

Affiliations
  • 1Department of Internal Medicine, Gachon University Gil Hospital, Gachon University of Medicine and Science, Incheon, Korea. jhchang@gilhospital.com
  • 2Department of Pathology, Gachon University Gil Hospital, Gachon University of Medicine and Science, Incheon, Korea.

Abstract

Kaposi's sarcoma (KS) is an unusual multifocal neoplasm of vascular endothelial cell origin. The trunk, arms, head, and neck are the most common sites. It is common in men and has four distinct variants: classic, Africa-endemic, immunosuppressive drug-associated, and acquired immunodeficiency syndrome-associated KS. KS appears to develop immunosuppressed patients, but is uncommon in patients on dialysis. A 79-year-old man on hemodialysis for 2 months presented with pruritus over the entire body and multiple, discrete, variable-sized, dark blue papulonodules (papuloplaques, maculopapules) on the left arm and shoulder. A biopsy specimen form the left arm showed spindle cells with slit-like spaces and extravasated red blood cells. The specimen was positive for CD 34 antigen, and human herpesvirus 8 was detected. We report a case of KS that occurred in a 79-year-old patient on hemodialysis.

Keyword

Kaposi sarcoma; Hemodialysis; HHV-8

MeSH Terms

Aged
Arm
Biopsy
Dialysis
Endothelial Cells
Erythrocytes
Head
Herpesvirus 8, Human
Humans
Male
Neck
Pruritus
Renal Dialysis
Sarcoma, Kaposi
Shoulder
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