Korean J Med.
2003 Nov;65(Suppl 3):S841-S843.
Two cases of pancytopenia induced by ticlopidine
- Affiliations
-
- 1Department of Internal Medicine, College of Medicine, Chosun University, Gwangju, Korea. chchung@mail.chosun.ac.kr
Abstract
- Ticlopidine is an inhibitor of platelet aggregation used in the management and prevention of thromboembolic disorders. Hematological toxicity is one of the most important side effects of ticlopidine, including neutropenia, thrombocytopenia and more seriously aplastic anemia. We reported here two cases of very severe aplastic anemia developed after the use of ticlopidine. Both patients suffered from an acute cerebral infarction. Both patients developed pancytopenia 56 days and 51 days after treatment with 500 mg of ticlopidine daily. Both patients were hospitalized and received empiric antibiotic therapy and G-CSF. Twenty-three days and thirty days after the withdrawal of ticlopidine, the hematologic parameters of each patient improved.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Severe Cholestatic Jaundice and Subsequent Pancytopenia Associated with Ticlopidine
- A Case of Aplastic Anemia Associated with Ticlopidine
- Severe aplastic anemia induced by ticlopidine: report of two cases
- Four cases of ticlopidine-induced cholestatic hepatitis
- A Case of Ticlopidine-Induced Cholastatic Jaundice
