Korean J Hematol.  2009 Sep;44(3):144-147. 10.5045/kjh.2009.44.3.144.

A Case of Acute Myeloblastic Leukemia in a Patient with Behcet's Disease

• Cha DH
• Kim SK
• Kim HJ
• Lee N
• Nam HS
• Choi BG
• Lee HW
• Kim SG
• Choi YJ
• Chung JS
• Cho GJ

• KMID: 2252132
• DOI: http://doi.org/10.5045/kjh.2009.44.3.144

Abstract

Behcet's disease is a relapsing inflammatory disorder characterized by vasculitis of unknown cause and has been reported rarely in association with malignant diseases. In most cases the autoimmune nature of Behcet's disease and the long-term immunosuppressive therapy for disease control have been proposed to be responsible for malignant transformation. Although a few cases of various solid tumor and myelodysplastic syndrome have been reported in association with Behcet's disease, acute leukemia has seldom been associated with Beh?et's disease in Korea. We report a case of 38-year-old man with acute myeloblastic leukemia association with a Behcet's disease who had not received long-term treatment.

Keyword

Behcet's disease; Acute myeloblastic leukemia

MeSH Terms

Acute Disease
Adult
Humans
Korea
Leukemia
Leukemia, Myeloid, Acute
Myelodysplastic Syndromes
Vasculitis

Figure

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  Fig. 1. The bone marrow aspirate shows myeloblastic cells (Wright Giemsa ×1,000).

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  Fig. 2. The bone marrow biopsy shows myeloblastic cells (H&E ×100).

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  Fig. 3. The karyogram shows hyperdiploidy clones (arrows), 52, XY,+8, +10, +12, +18, +21, +22.

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