Korean J Dermatol.  2014 Mar;52(3):173-177.

Four Cases of Severe Fever with Thrombocytopenia Syndrome Occurring in Jeju

Affiliations
  • 1Department of Dermatology, Jeju National University School of Medicine, Jeju, Korea. rulid@jejunu.ac.kr
  • 2Department of Internal Medicine, Jeju National University School of Medicine, Jeju, Korea.

Abstract

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by a novel SFTS bunyavirus (SFTSV), a member of the genus Phlebovirus in the family Bunyaviridae. SFTSV is believed to be transmitted by Haemaphysalis longicornis. Common symptoms of SFTS include high fever, vomiting, diarrhea, thrombocytopenia, leukocytopenia, and multi-organ failure with an average case-fatality rate of 12~30%. In 2009, SFTS was firstly reported in China. In 2013, 27 cases of SFTS were documented in Korea, and 6 cases were confirmed on Jeju Island. Although the pathogenesis and transmission mode of SFTS remain unclear, SFTS is now considered endemic in East Asia. Accordingly, SFTS needs to be differentiated from scrub typhus, leptospirosis, and hemorrhagic fever with renal syndrome. We here report 4 cases of SFTS preceded by a tick bite, which were in need of a differential diagnosis of scrub typhus.

Keyword

Severe Fever with Thrombocytopenia Syndrome

MeSH Terms

Bunyaviridae
China
Communicable Diseases, Emerging
Diagnosis, Differential
Diarrhea
Far East
Fever*
Hemorrhagic Fever with Renal Syndrome
Humans
Korea
Leptospirosis
Leukopenia
Phlebovirus
Scrub Typhus
Thrombocytopenia*
Tick Bites
Vomiting
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