Korean J Hepatobiliary Pancreat Surg.  2004 Sep;8(3):202-205.

Nesidioblastosis with Hyperinsulinemic Hypoglycemia in Adult

Affiliations
  • 1Department of General Surgery, Ilsan Paik Hospital, Inje University, Ilsan, Korea. cnkim@ilsanpaik.ac.kr

Abstract

Nesidioblastosis is a term that describes the prolonged differentiation of islets of Langerhan's cells from the epithelium of the pancreatic duct. Nesidioblastosis is a primarily childhood disease, which is often associated with hyperinsulinemic hypoglycemia, but rarely found in adults. A 62-year-old man with hyperinsulinemic hypoglycemia complained of general weakness and mental change while fasting. Abdominopelvic CT, celiac angiography, intra-arterial calcium stimulation test and endoscopic ultrasonography did not reveal any tumor in the pancreas. A subtotal pancreatectomy (nearly 80% of pancreas was removed) was then carried out. He was diagnosed with nesidioblastosis inform the pathology after the operation. Herein, our experience of a 62-year-old Nesidioblastosis patient is reported.

Keyword

Nesidioblastosis; Hyperinsulinemic Hypoglycemia

MeSH Terms

Adult*
Angiography
Calcium
Endosonography
Epithelium
Fasting
Humans
Hypoglycemia*
Middle Aged
Nesidioblastosis*
Pancreas
Pancreatectomy
Pancreatic Ducts
Pathology
Calcium
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