Korean J Anesthesiol.  2003 Jul;45(1):153-156. 10.4097/kjae.2003.45.1.153.

Antagonistic Effect of Flumazenil on the Prolonged Oversedation after Sevoflurane Based Anesthesia: A case report

Affiliations
  • 1Department of Anesthesilology and Pain Medicine, Wooridul Spine Hospital, Seoul, Korea. usu97@naver.com
  • 2Department of Neurosurgery, Wooridul Spine Hospital, Seoul, Korea.

Abstract

Prolonged oversedation occurs frequently in postoperative care units, and sometimes delays transfer to normal units. Flumazenil is a known reversal drug for benzodiazepines, and is used to reverse the oversedation caused by benzodiazepines. However, we found that flumazenil was effective in a case of sevoflurane induced oversedation. A prolonged oversedation of 90 minutes occurred after sevoflurane anesthesia without benzodiazepine at a postoperative care unit. Immediately after an intravenous injection of flumazenil, the patient fully awoke and was oriented.

Keyword

flumazenil; oversedation; sevoflurane

MeSH Terms

Anesthesia*
Benzodiazepines
Flumazenil*
Humans
Injections, Intravenous
Postoperative Care
Benzodiazepines
Flumazenil
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