Korean J Asthma Allergy Clin Immunol.  2006 Sep;26(3):254-258.

Two Cases of Serum Sickness Reaction Induced by Bee Stings

Abstract

The usual reactions after an insect sting are mild redness and swelling at the stinging site, and the most serious reaction is anaphylaxis. There have been isolated reports of late-onset reactions, such as vasculitis, nephritis, neuritis, and serum sickness, occuring in association with an insect sting. Late-onset reactions, including serum sickness, occur much less frequently. We report 2 individuals who developed serum sickness reaction after bee stings. A 35-year-old male, a family member of beekeeper, had stung frequently. About 10 days after bee stings, he complained of fever, migratory polyarthralgia, erythematous skin rash, and myalgia. High levels of specific IgE to bee venom were detected by the radioallergosorbent test (RAST). The other patient was a 25-year-old male who presented with urticaria, angioedema, arthralgia, myalgia, fever, and skin rash about 7 days after a bee sting. He also had high titers of specific IgE to bee venom. We here report two cases of serum sickness reaction caused by bee stings.


MeSH Terms

Adult
Anaphylaxis
Angioedema
Arthralgia
Bee Venoms
Bees*
Bites and Stings*
Exanthema
Fever
Humans
Immunoglobulin E
Insect Bites and Stings
Male
Myalgia
Nephritis
Neuritis
Radioallergosorbent Test
Serum Sickness*
Urticaria
Vasculitis
Bee Venoms
Immunoglobulin E
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