J Pathol Transl Med.  2016 Jan;50(1):78-81. 10.4132/jptm.2015.07.03.

Indeterminate Dendritic Cell Tumor: A Case Report of a Rare Langerhans Cell Lineage Disease

• Roh J
• Kim SW
• Park CS

• KMID: 2211411
• DOI: http://doi.org/10.4132/jptm.2015.07.03

Abstract

No abstract available.

MeSH Terms

Cell Lineage*
Dendritic Cells*

Figure

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  Fig. 1. (A) An ill-defined, 1.2-cm, round, erythematous subcutaneous nodule on the left flank. (B) The ill-defined tumor is mainly located in the dermis and subcutis. The margin of the tumor is marked by arrowheads.

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  Fig. 2. (A) There is patchy infiltration by aggregates of the tumor cells. Tumor cells are usually monotonous and have indistinct cell borders. Clusters of lymphocytes are admixed with tumor cells in focal areas without eosinophils. (B) The constituent cells have ovoid cell morphology with abundant eosinophilic cytoplasm. (C) Their nuclei are oval and sometimes indented. Nuclear grooves are frequently seen. Although occasional enlarged nuclei are identified, mitoses are rarely seen. (D) There is no epidermal involvement.

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  Fig. 3. The neoplastic cells diffusely express CD1a (A) and S100 protein (B). (C) Langerin (CD207) is typically negative. (D) No Birbeck granules are seen on transmission electron microscopy (×8,000).

Reference

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