J Korean Pediatr Soc.  1996 Sep;39(9):1320-1325.

A Case of Pseudomembranous Colitis due to Clostridium difficile

Affiliations
  • 1Department of Pediatrics, Catholic University Medical College, Seoul, Korea.

Abstract

Pseudomembranous colitis may result from abnormal growth of toxigenic strains of Clostridium difficile associated with antibiotic-induced alteration of the colonic microbiologic flora. C. difficile, a spore forming gram positive obligate anaerobic bacillus, is part of the normal flora and known to be the major cause of pseudomembranous colitis. We experienced a case of pseudomembranous colitis in a 14-month-old male presented with bloody mucoid diarrhea and fever who had received broad spectrum antibiotics for the treatment of pneumonia. This case was diagnosed with sigmoidoscopy and confirmed by isolation of the organism on culture with selective media TCCFA. All antibiotics were discontinued and vancomycin was administrated orally. He showed a good response.

Keyword

Pseudomembranous Colitis; Clostridium difficile

MeSH Terms

Anti-Bacterial Agents
Bacillus
Clostridium difficile*
Clostridium*
Colon
Diarrhea
Enterocolitis, Pseudomembranous*
Fever
Humans
Infant
Male
Pneumonia
Sigmoidoscopy
Spores
Vancomycin
Anti-Bacterial Agents
Vancomycin
Full Text Links
  • KJP
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr