J Korean Ophthalmol Soc.
2003 Jan;44(1):208-214.
The Effects of ADCON(R)-L on the Adhesion after Strabismus Surgery
- Affiliations
-
- 1Department of Ophthalmology, College of Medicine Chungbuk National University, Korea. mychoi@med.chungbuk.ac.kr
- 2Chungbuk National University Medical Research Institute, Cheongju, Korea.
Abstract
- PURPOSE
We investigated the effectiveness of ADCON-L in reducing the formation of adhesion after strabismus surgery in a rabbit model. METHODS: Bilateral recessions of superior rectus muscle (SR) were performed on 18 rabbits. ADCON-L was applied beneath and over the SR in 9 rabbits, while operative fields in the others were irrigated with a balanced salt solution (BSS). The degree of adhesion was recorded at 3 weeks postoperatively. All eyes were enucleated and histopathologic examination was done at 4 weeks postoperatively, and the degree of fibrous proliferation and inflammation were evaluated. RESULTS: A significant reduction in the degree of adhesion and fibrosis was noted in eyes treated with ADCON-L as compared with in those irrigated with BSS (p=0.003, p=0.028). However there was no statistical significance in the degree of inflammation between two groups (p=0.114). CONCLUSIONS: This study suggests that ADCON-L is effective in reducing postoperative adhesion for as long as 4 weeks after strabismus surgery in rabbits.
Keyword
MeSH Terms
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Delayed Detected Unexpected Complication of ADCON-L(R) Gel in Lumbar Surgery
- Combined study on the causes of strabismus after the retinal surgery
- Effects of 5-Fluorouracil on Delayed Adjustment in Experimental Strabismus Surgery
- Availability of Polyethylene Film for Reduction of Postoperative Adhesion in Adjustable Strabismus Surgery in Rabbits
- The Effect of Absorbable Cellulose(Interceed, TC7) in Prevention of Adhesion in Strabismus Surgery in Rabbits
