J Korean Rheum Assoc.  1995 Jul;2(2):187-191.

A Case of Primary Sjogren's Syndrome Presenting as Adie's Syndrome

• Kim SH
• Kim YH
• Cho YS
• Kim C
• Choi SW
• Yoo B
• Lee MC
• Moon HB

Abstract

Sjogren's syndrome is a hererogenous autoimmune disease characterized by progressive destruction of the exocrine glands and accompanied by a variety of autoimmune phenomena. Sjogren's syndrome patients can develop symptoms of ocular and oral dryness as well as extraglandular complications including central and peripheral nervous system disease. Sometimes neuropathy precedes the diagnosis of Sjogren's syndrome. Adiets syndrome is characterized by tonic pupil and the absence of tendon reflex. Sweating abnormality and chronic peripheral polyneuropathy can also be present. We report a case of primary Sjogren's syndrome preceded by Adie's syndrome with peripheral neuropathy. A 26-year-old woman was admitted for photophobia and paresthesia. On examination, her pupils were anisocoric and did not react to light but constricted promptly to pilocarpin. Sensation decreased on her left side of body and deep' tendon reflexes were absent. Biopsy of minor salivary gland demonstrated infiltration by lymphocyte consistent with Sjogren's syndrome, but Schirmer test was negative. So she was diagnosed as Adie's syndrome with peripheral neuropathy. Five month later she complained of dry eye and dizziness. Rose bengal staining was positive. Sjogren's syndrome was diagnosed and she was discharged with local therapy for the sicca symptoms.

Keyword

Sjogren's syndrome; Adie's syndrome

MeSH Terms

Adie Syndrome*
Adult
Autoimmune Diseases
Biopsy
Diagnosis
Dizziness
Exocrine Glands
Female
Humans
Lymphocytes
Paresthesia
Peripheral Nervous System Diseases
Photophobia
Polyneuropathies
Pupil
Reflex, Stretch
Rose Bengal
Salivary Glands, Minor
Sensation
Sjogren's Syndrome*
Sweat
Sweating
Tonic Pupil
Rose Bengal