J Korean Soc Ther Radiol.  1983 Mar;1(1):5-10.

An Experimental Study on Late Change of the Irradiated Lung

• Byun HS
• Park CI
• Han MC

Abstract

To evaluate late change of irradiated lung, a total of 60 rats was irradiated on right lungfield with a single dose of 2000 rads using Co-0 teletherapy unit. Follow-p roentgenographic and histopathologic study was performed three, six and twelve months after irradiation in each group of 20 rats. The results were as follows: 1.Chest roentgenographic findings in the order of frequency were pneumonic consolidation, atelectasis, and pleural effusion in 3-onth follow-p group; atelectasis, fibrostreaky infiltration, and pneumonic consolidation in 6-onth follow-p; and normal, and normal, and atelectasis in 12-onths follow-p group. 2. Main histopathological findings were alveolar and interstitial exudates, and diffuse infiltration of inflammatory cells in 3-onth follow-p group; thickening of interstitium and vascular wall in 6-onth follow-p group; and interstitial fibrosis in 12-onth follow-p group.

MeSH Terms

Animals
Exudates and Transudates
Fibrosis
Lung*
Pleural Effusion
Pulmonary Atelectasis
Rats