J Korean Soc Ther Radiol.  1993 Jun;11(1):59-68.

Postoperative Radiation Therapy of Craniopharyngioma

• Shin KH
• Yun HG
• Kim IH
• Park CI
• Cho BK

Abstract

Between December 1979 and September 1989, 23 patients with craniopharyngioma who underwent surgery and postoperative radiation therapy were retrospectively evaluated to assess the efficacy of this management at the Department of Therapeutic Radiology, Seoul National University Hospital. Total removal of tumor was attempted in all patients. Of these, surgeons tried total removal in eight patients, but revealed residual mass by postoperative CT, and partial removal was done in 15 patients. The morphology of tumor on the operative finding was grouped into three types : cystic 13 (57%), solid 4 (17%), and mixed 6 (26%). Cystic type was predominant in< or =20 years old group. Actuarial overall survival rates at 5 and 10 years were 95% and 81% respectively and actuarial tumor control rates were 74% and 50%. Surgical extent was not related to the survival rates(p=0.41). Pediatric and adolescent Patients(age of< or =20 year) had a trend of better survival than that of adult patients(p=0.10). The results indicated that limited surgical excision followed by radiation therapy is recommended when total excision is not possible.

Keyword

Craniopharyngioma; Radiation therapy; Survival rate

MeSH Terms

Adolescent
Adult
Craniopharyngioma*
Humans
Radiation Oncology
Retrospective Studies
Seoul
Survival Rate