J Korean Assoc Oral Maxillofac Surg.  1997 Jul;23(3):507-514.

PRESENCE OF VIMENTIN IMMUNOREACTIVE FILAMENTS IN THE CELLS OF MANDIBULAR FOSSA FBROUS LAYER OF RAT WITH AGING

• Hong LW
• Song JC
• Kim CS

Abstract

The purpose of this study was to investigate what the intermediate filaments in the cells of rat mandibular fossa fibrous layer are and any relationships between the presence of these filaments and aging. Mandibular fossae of 4 groups of rats(14-day, 28-day, 55-day and adult groups) were removed on bloc and processed for immunostaining and were subjected to light microscopic examination. The results were as follows : In 14-day group, there were no immunoreactive cells in fibrous layer of mandibular condyle articular surface. But in 28-day group, many immunoreactive cells were seen in fibrous layer, especially central portion of articular surface of mandibular fossa. These cells were fusiform shaped and immunoreactivities were seen in the cytoplasm around the nucleus. In 55-day group many immunoreactive cells were seen in fibrous layer of mandibular fossa. These cells were fusiform shaped and distributed evenly in central portion of this fibrous layer. Immunoreactivities were seen in the cytoplasm around the nucleus. In adult group, the results were similar to 55-day group, Many immunoreactive cells were seen in fibrous layer of mandibular fossa especially central portion. According to these results, vimentin immunoreactive filaments appear with aging and increment of mechanical load associated with incision or mastication.

MeSH Terms

Adult
Aging*
Animals
Cytoplasm
Humans
Intermediate Filaments
Mandibular Condyle
Mastication
Rats*
Vimentin*
Vimentin