- Recent Advances in Molecular Basis of Lung Aging and Its Associated Diseases
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Kang MJ
- KMID: 2471886
- Tuberc Respir Dis.
- 2020 Apr;83(2):107-115.
- doi: 10.4046/trd.2020.0003
Aging is often viewed as a progressive decline in fitness due to cumulative deleterious alterations of biological functions in the living system. Recently, our understanding of the molecular mechanisms underlying... -
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- Cellular Senescence in Arterial Diseases
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Shimizu I, Minamino T
- KMID: 2470802
- J Lipid Atheroscler.
- 2020 Jan;9(1):79-91.
- doi: 10.12997/jla.2020.9.1.79
Cell-proliferation potency is limited, as cells cannot proceed through the cell cycle continually. Instead, they eventually show an irreversible arrest of proliferation, commonly referred to as cellular senescence. Following the... -
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- Quercetin-induced apoptosis ameliorates vascular smooth muscle cell senescence through AMP-activated protein kinase signaling pathway
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Kim SG, Sung JY, Kim JR, Choi HC
- KMID: 2466571
- Korean J Physiol Pharmacol.
- 2020 Jan;24(1):69-79.
- doi: 10.4196/kjpp.2020.24.1.69
Aging is one of the risk factors for the development of cardiovascular diseases. During the progression of cellular senescence, cells enter a state of irreversible growth arrest and display resistance... -
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- Upcoming Aging Society and Men's Health: Focus on Clinical Implications of Exercise and Lifestyle Modification
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Park B, Lee YJ
- KMID: 2465407
- World J Mens Health.
- 2020 Jan;38(1):24-31.
- doi: 10.5534/wjmh.180103
Recent epidemiological research has indicated that men have increased health risks due to biological and social factors. Research in the area of men's health has been focused on disease events... -
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- A Comparative Study on the Factors Affecting the Successful Aging between Users and Non-users of Kyung-ro-dang for Community Care Policy Activation
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Song GR, Nam EW, Jin KN
- KMID: 2470449
- Health Policy Manag.
- 2019 Dec;29(4):412-421.
- doi: 10.4332/KJHPA.2019.29.4.412
BACKGROUND: The purpose of this study was to identify the status of Successful Aging among the elderly aged 65 and over in rural areas and to compare factors related with... -
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- Complications of Spine Surgery in Elderly Japanese Patients: Implications for Future of World Population Aging
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Umekawa M, Takai K, Taniguchi
- KMID: 2469057
- Neurospine.
- 2019 Dec;16(4):780-788.
- doi: 10.14245/ns.1938184.092
OBJECTIVE: To analyze the relationship between age and perioperative complications of spine surgery in a Japanese cohort with the longest average life expectancy in the world. METHODS: Patients with spinal stenosis... -
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- Autophagy, Cellular Aging and Age-related Human Diseases
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Cheon SY, Kim H, Rubinsztein DC, Lee JE
- KMID: 2468882
- Exp Neurobiol.
- 2019 Dec;28(6):643-657.
- doi: 10.5607/en.2019.28.6.643
Macroautophagy/autophagy is a conserved degradation system that engulfs intracytoplasmic contents, including aggregated proteins and organelles, which is crucial for cellular homeostasis. During aging, cellular factors suggested as the cause of... -
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- Changes in Glucose Metabolism with Aging
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Hong EG
- KMID: 2468008
- J Korean Diabetes.
- 2019 Dec;20(4):215-219.
- doi: 10.4093/jkd.2019.20.4.215
The increasing risk of glucose intolerance and diabetes associated with aging is well established. However, it is difficult to determine whether changes in glucose metabolism result from biological aging itself... -
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- Aging and the Immune System: the Impact of Immunosenescence on Viral Infection, Immunity and Vaccine Immunogenicity
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Oh SJ, Lee JK, Shin OS
- KMID: 2466607
- Immune Netw.
- 2019 Dec;19(6):e37.
- doi: 10.4110/in.2019.19.e37
Immunosenescence is characterized by a progressive deterioration of the immune system associated with aging. Multiple components of both innate and adaptive immune systems experience aging-related changes, such as alterations in... -
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- Effects of an Aging Management Program for Middle-aged Women on Resilience and Successful Aging
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Jung H, Sung KM
- KMID: 2465981
- Korean J Women Health Nurs.
- 2019 Dec;25(4):392-408.
- doi: 10.4069/kjwhn.2019.25.4.392
PURPOSE: The purpose of this study was to examine the effects of an aging management program on the resilience and successful aging of middle-aged women. METHODS: A quasi-experimental study with a... -
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- Etoposide Induces Mitochondrial Dysfunction and Cellular Senescence in Primary Cultured Rat Astrocytes
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Bang M, Kim DG, Gonzales E, Kwon KJ, Shin CY
- KMID: 2462880
- Biomol Ther.
- 2019 Nov;27(6):530-539.
- doi: 10.4062/biomolther.2019.151
Brain aging is an inevitable process characterized by structural and functional changes and is a major risk factor for neurodegenerative diseases. Most brain aging studies are focused on neurons and... -
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- Advantage of Dairy for Improving Aging Muscle
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Du Y, Oh C, No J
- KMID: 2459811
- J Obes Metab Syndr.
- 2019 Sep;28(3):167-174.
- doi: 10.7570/jomes.2019.28.3.167
The risk of sarcopenia increases with aging. Malnutrition in the elderly population is an important risk factor for sarcopenia. Calcium (Ca), phosphate (P), vitamin D and protein are key nutrients... -
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- The Influence of Negative Mental Health on the Health Behavior and the Mortality Risk: Analysis of Korean Longitudinal Study of Aging from 2006 to 2014
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Jun ER, Kim SH, Cho YJ, Kim YA, Lee JY
- KMID: 2459567
- Korean J Fam Med.
- 2019 Sep;40(5):297-306.
- doi: 10.4082/kjfm.18.0068
BACKGROUND: Several studies have shown that negative mental health increases risky health behavior and mortality risk. We investigated the relationship between mental health and health behavior, and the causal association... -
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- Optical coherence tomography angiography in preclinical neuroimaging
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Choi WJ
- KMID: 2470026
- Biomed Eng Lett.
- 2019 Aug;9(3):311-325.
- doi: 10.1007/s13534-019-00118-8
Preclinical neuroimaging allows for the assessment of brain anatomy, connectivity, and function in laboratory animals, such as mice and this imaging field has been a rapidly growing aimed at bridging... -
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- Prevention of sepsis in an aging society
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Kang Y
- KMID: 2457681
- Acute Crit Care.
- 2019 Aug;34(3):221-222.
- doi: 10.4266/acc.2019.00612
No abstract available. -
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- Socioeconomic Vulnerability, Mental Health, and Their Combined Effects on All-Cause Mortality in Koreans, over 45 Years: Analysis of Korean Longitudinal Study of Aging from 2006 to 2014
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Kim EM, Kim SH, Lee GH, Kim YA
- KMID: 2454759
- Korean J Fam Med.
- 2019 Jul;40(4):227-234.
- doi: 10.4082/kjfm.18.0137
BACKGROUND: We evaluated the effects of socioeconomic factors and psychosocial factors, both individually and combined, on all-cause mortality risk (mortality risk). METHODS: We conducted an 8-year (2006–2014) longitudinal analysis of 10,247... -
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- Association of Nutritional Status with Cognitive Stage in the Elderly Korean Population: The Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's Disease
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Jang JW, Kim Y, Choi YH, Lee JM, Yoon B, Park KW, Kim SE, Kim HJ, Yoon SJ, Jeong JH, Kim EJ, Jung NY, Hwang J, Kang JH, Hong JY, Choi SH
- KMID: 2451111
- J Clin Neurol.
- 2019 Jul;15(3):292-300.
- doi: 10.3988/jcn.2019.15.3.292
BACKGROUND AND PURPOSE: Epidemiological studies have suggested the presence of strong correlations among diet, lifestyle, and dementia onset. However, these studies have unfortunately had major limitations due to their inability... -
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- Angiotensin II Type 1 Receptor Blocker, Fimasartan, Reduces Vascular Smooth Muscle Cell Senescence by Inhibiting the CYR61 Signaling Pathway
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Kim I, Park CS, Lee HY
- KMID: 2450393
- Korean Circ J.
- 2019 Jul;49(7):615-626.
- doi: 10.4070/kcj.2018.0379
BACKGROUND AND OBJECTIVES: Angiotensin II (Ang II) has been suggested to accelerate vascular senescence, however the molecular mechanism(s) remain unknown. METHODS: We cultured human coronary artery smooth muscle cells (hCSMCs) and... -
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- How Does Obesity and Physical Activity Affect Aging?: Focused on Telomere as a Biomarker of Aging
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Shin YA
- KMID: 2459821
- J Obes Metab Syndr.
- 2019 Jun;28(2):92-104.
- doi: 10.7570/jomes.2019.28.2.92
Obesity is known to continuously increase systemic inflammation and oxidative stress, leading to shorter telomere length. However, research regarding the correlation between physical activity, exercise, obesity, and telomere length is... -
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- Emerging Issues in Cerebral Palsy Associated With Aging: A Physiatrist Perspective
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Yi YG, Jung SH, Bang MS
- KMID: 2453913
- Ann Rehabil Med.
- 2019 Jun;43(3):241-249.
- doi: 10.5535/arm.2019.43.3.241
The population of adults diagnosed with cerebral palsy (CP) is increasing along with the survival rate of children born with the disability. Adults with CP need health services for the... -
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