J Korean Assoc Oral Maxillofac Surg.  2011 Feb;37(1):72-76. 10.5125/jkaoms.2011.37.1.72.

Polymorphous low-grade adenocarcinoma on hard palate: case report

• Shin YM
• Choi SY
• Kim JW
• Byeon KJ
• Kim CS

• KMID: 2189810
• DOI: http://doi.org/10.5125/jkaoms.2011.37.1.72

Abstract

Polymorphous low-grade adenocarcinomas (PLGA) are distinctive salivary gland neoplasms with a propensity to arise from the minor salivary glands. The most frequent location of PLGA is the palate, even though other locations have been described. Previously used terms for PLGA include lobular carcinoma and terminal duct carcinoma. Although the frequency of the tumor is unknown, the recognition of PLGA as an individual tumor has increased with the establishment of specific histopathological criteria characterizing the PLGA. The first choice of treatment is a wide surgical excision including the subjacent bone if necessary. The prognosis is generally good and the recurrence rate ranges from 17% and 22%. Distant metastases is unusual (9%) but occur mainly in the regional lymph nodes. This is a case report of a 67 year old female patient with PLGA who was treated with a wide excision by layers (2 stage) of the lesion including the surrounding bone. We present this case with a review of the relevant literature.

Keyword

Polymorphous low-grade adenocarcinomas; Excision by layers

MeSH Terms

Adenocarcinoma
Carcinoma, Lobular
Female
Humans
Lactic Acid
Neoplasm Metastasis
Palate
Polyglycolic Acid
Prognosis
Recurrence
Salivary Gland Neoplasms
Salivary Glands, Minor
Lactic Acid
Polyglycolic Acid

Figure

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  Fig. 1. Ulcerative lesion on right palate was showed at first visit.

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  Fig. 2. PET-CT: without significant focal FDG uptake in right palate.(PET-CT: positron emission tomography-computed tomography, FDG: fluorodeoxyglucose)

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  Fig. 3. Excised mass of tumor and underlying bone.

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  Fig. 4. Intraoral view of postoperation state.

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  Fig. 5. Ten months after surgery: operation site is unremarkable.

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  Fig. 6. Histological overview.(H&E staining, original magnification 4×10)

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  Fig. 7. Schematic view of monobloc excision.

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  Fig. 8. Schematic view of excision by layers.

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  Fig. 9. Postoperative Water's view.

Reference

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