J Korean Orthop Assoc.  2007 Oct;42(5):684-687. 10.4055/jkoa.2007.42.5.684.

Intradural Solitary Fibrous Tumor in the Thoracic Spine: A Case Report

Affiliations
  • 1Department of Orthopaedic Surgery, Pusan National UniversitySchool of Medicine, Busan, Korea. jungsublee@pusan.ac.kr
  • 2Department of Pathology, Pusan National UniversitySchool of Medicine, Busan, Korea.

Abstract

A fibrous tumor is a rare tumor that arises mainly in the visceral pleura but can occur in many locations throughout the body including the soft tissue, upper respiratory tract, peritoneum, retroperitoneum, periosteum, and intracranial portion. Recently, a solitary fibrous tumor was found in the central nervous system. However, the incidence of an intradural solitary fibrous tumor is quite low and there are no domestic reports of such cases. We report a case of intradural extramedullary solitary fibrous tumor of the thoracic spine. A favorable clinical result was obtained using surgical treatment. The immunohistological findings revealed the tumor to be reactive to vimentin and CD34 but negative to the S-100 protein, alpha smooth muscle actin and desmin.

Keyword

Solitary fibrous tumor; Thoracic spine

MeSH Terms

Actins
Central Nervous System
Desmin
Incidence
Muscle, Smooth
Periosteum
Peritoneum
Pleura
Respiratory System
S100 Proteins
Solitary Fibrous Tumors*
Spine*
Vimentin
Actins
Desmin
S100 Proteins
Vimentin

Figure

  • Fig. 1 Sagittal (upper row) and axial (lower row) T1 weighted magnetic resonance images show an irregular hypointense mass at the T7-8 level (left column). T2 weighted images show intermediate signal intensity area (right column).

  • Fig. 2 Intraoperative photograph shows a whitish fibrotic mass attached to the spinal cord.

  • Fig. 3 Microscopic appearances of the fibrous tumor. Photomicrograph of the specimen show spindle cell proliferation and dense intracellular collagen deposition (A: HE stain, ×40 and B: HE stain, ×400). Immunohistochemical staining shows the tumor cells are focally positive for CD34 (C) and strongly positive for vimentin (D).


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