J Korean Orthop Assoc.  2009 Dec;44(6):686-690. 10.4055/jkoa.2009.44.6.686.

Osteomyelitis due to Nontuberculous Mycobacterium in Immunocompetent Children: Report of Two Cases

Affiliations
  • 1Department of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul, Korea. inhoc@snu.ac.kr
  • 2Department of Orthopaedic Surgery, Chonbuk National University College of Medicine, Jeonju, Korea.

Abstract

Osteomyelitis caused by nontuberculous mycobacterium (NTM) is rare in immunocompetent children, and is often difficult to differentiate from a bone tumor, juvenile rheumatoid arthritis, soft-tissue inflammation and subacute osteomyelitis. We report NTM osteomyelitis in immunocompetent children that developed at the left distal femoral epiphysis in a 24-month-old boy and at both tali in a 7-year-old boy.

Keyword

Nontuberculous mycobacterium; Osteomyelitis

MeSH Terms

Arthritis, Juvenile Rheumatoid
Child
Epiphyses
Humans
Inflammation
Nontuberculous Mycobacteria
Osteomyelitis
Preschool Child

Figure

  • Fig. 1 Case 1. Plain radiograph shows radiolucent lesion with some irregularity at the distal femoral epiphysis and mild soft tissue swelling around distal thigh.

  • Fig. 2 Case 1. Contrast enhanced T1-weighted MR images show bony lesion with enhancement at the distal femoral epiphysis.

  • Fig. 3 Case 1. Plain radiographs. (A) At 3 months after latest operation. Well-defined osteolytic lesion at left distal femur metaphysis and epiphysis. (B) 9 months after latest operation. Showing a sclerotic demarcation. (C) 18 months after latest operation. Well healing status of osteomyelitis without an evidence of recurrence.

  • Fig. 4 Case 2. Plain radiographs show destructive bony lesion in both talus and calcaneus with ankle joint swelling. Plain radiographs of the right (A, C) and left ankle (B, D).

  • Fig. 5 Case 2. Contrast enhanced T1-weighted MR images show bone marrow signal change at the right talus and calcaneus with enhancement and joint effusion with strong enhancement of synovial membrane.


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