J Korean Androl Soc.  1991 Dec;9(2):111-115.

Norepinephrine level of cavernosal blood in psychogenic impotence

  • 1Department of Urology, College of Medicine, Chung Ang University, Seoul, Korea.
  • 2Department of Clinical Pathology, College of Medicine, Chung Ang University, Seoul, Korea.


The present study was designed to investigate whether the secretion of endogenous catecholamine might be involved in the erection response of psychogenic impotence. We measured epinephrine(E) and norepinephrine(NE) levels in systemic and penile blood during papaverine test, and compared them between positive and negative responders of psychogenic impotence to papaverine test as well as among the normal potent volunteers, psychogenic and vasculogenic impotence patients. The NE level in the penile blood was higher in the psychogenic impotence than in the normal control and vasculogenic impotence(p<0.01), and significantly higher in negative responders than in positive responders of the psychogenic impotence(p<0.001). There was no significant difference in the E level of both systemic and penile blood among the groups. Therefore, psychogenic erection dysfunction may be derived from secretion of cavernosal norepinephrine.

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