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Incidence of Hypotension after Discontinuation of Norepinephrine or Arginine Vasopressin in Patients with Septic Shock: a Systematic Review and Meta-Analysis

Song JU, Lee J, Park HK, Suh GY, Jeon K

BACKGROUND: There has been no consensus regarding the discontinuation order of vasopressors in patients recovering from septic shock treated with concomitant norepinephrine (NE) and arginine vasopressin (AVP). The aim of...
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Anti-allodynic Efficacy of NMDA Antagonist Peptide and Noradrenaline Alone and in Combination in Rodent Neuropathic Pain Model

Nasirinezhad F, Hosseini M, Salari S

BACKGROUND: The present experiment was conducted to identify the cooperative effect of serine histogranin (SHG) and noradrenaline in alleviating peripheral neuropathic pain. METHODS: Chronic constriction injury of the right sciatic nerve...
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Association Study between Norepinephrine Transporter Gene Polymorphism and Schizophrenia in a Korean Population

Choo M, Hwang JA, Jeon SW, Oh SY, Yoon HK, Lee HJ, Kim YK

OBJECTIVE: We aimed to investigate possible associations between three norepinephrine transporter gene (SLC6A2) single nucleotide polymorphisms (T182C, A3081T, and G1287A) and schizophrenia. Also, we investigated the relationships of those polymorphisms...
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Duloxetine, a Selective Noradrenaline Reuptake Inhibitor, Increased Plasma Levels of 3-Methoxy-4-hydroxyphenylglycol but Not Homovanillic Acid in Patients with Major Depressive Disorder

Atake K, Yoshimura , Hori H, Katsuki A, Ikenouchi-Sugita A, Umene-Nakano W, Nakamura J

  • KMID: 2171127
  • Clin Psychopharmacol Neurosci.
  • 2014 Apr;12(1):37-40.
OBJECTIVE: We investigated the effects of duloxetine on the plasma levels of catecholamine metabolites and serum brain-derived neurotrophic factor (BDNF) in 64 patients with major depressive disorder (MDD). METHODS: Major depressive...
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Inhibitory Effects of Norepinephrine on the Potassium Current of Rat Medial Vestibular Nuclear Neurons

Jeong HS, Jang MJ, Huang M, Huh HR, Cho KH, Kim BC, Park JS

  • KMID: 1626909
  • J Korean Neurol Assoc.
  • 2005 Jun;23(3):363-367.
BACKGROUND: This study aimed to explore the effects of norepinephrine on the potassium currents of rat medial vestibular nuclear neurons by using the whole-cell patch clamp technique. METHODS: Sprague-Dawley rats...
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Effects of Norepinephrine on the Resting Activity of Medial Vestibular Nuclear Neurons in the Rat

Jeong HS, Huh HR, Huang M, Park JS

  • KMID: 2172335
  • Chonnam Med J.
  • 2005 Apr;41(1):14-18.
The purpose of this study is to clarify the increasing effects of norepinephrine on the spontaneous activity of medial vestibular nuclear neurons of the rat. Sprague-Dawley rats aged 14 to...
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Effect of Low Dose Norepinephrine Infusion on Myocardial Oxygen Consumption and Lactate Metabolism

Choi CS, Lee SS, Kim BJ, In JY, Huh JH, Lee Y, Yon JH, Moon HW

BACKGROUND: Norepinephrine infusion has been reported to be associated with adverse events in ischemic heart disease due to elevation of afterload and cardiac oxygen consumption. During coronary artery bypass graft,...
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Effect of Norepinephrine Irrigation in Primary Total Knee Replacement Arthroplasty

Cho WS, Kim JM, Ahn HS, Lee BS

  • KMID: 2399073
  • J Korean Orthop Assoc.
  • 2004 Jun;39(3):247-251.
PURPOSE: We studied the effect of norepinephrine irrigation during total knee replacement arthroplasty (TKRA) on blood loss reduction. MATERIALS AND METHODS: A prospective study of 30 patients who received TKRA...
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Effect of Pulmonary Artery Pressure on Changes in Right Ventricular Function according to Norepinephrine Infusion in Patients with Valvular Heart Disease

Kwak YL, Kim JY, Kim SH, Oh YJ, Lee JH, Lee KH, Bang SO

BACKGROUND: Increasing coronary perfusion pressure by using a vasopressor is one of the important treatment strategies in pulmonary hypertension. In present study, we evaluated whether chronic pulmonary hypertension influences the...
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The Effect of alpha2 Adrenergic Agonists and Norepinephrine on Mechanical Allodynia by Freund's Complete Adjuvant Induced Inflammation in Rats

Cheong MA, Kim HN, Jun JH, Kim KH, Suh JK, Hwang JH, Park PH, Key WY

BACKGROUND: The Freund's complete adjuvant (FCA)-induced inflammation may produce allodynia against a touch stimulus. The antiallodynic effects of brimonidine, a new selective alpha2 receptor agonist, and of rilmenidine, a new...
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Effects of Noradrenaline on the Membrane Potential of Prostatic Neuroendocrine Cells of Rat

Kim JH, Shin SY, Uhm DY, Kim SJ

  • KMID: 1607354
  • Korean J Physiol Pharmacol.
  • 2003 Feb;7(1):47-52.
The prostate gland contains numerous neuroendocrine cells that are believed to influence the function of the prostate gland. Our recent study demonstrated the expression of both alpha 1- and alpha...
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Effects of SP-6 Acupressure on Dysmenorrhea, Cortisol, Epinephrine and Norepinephrine in the College Students

Chang SB, Jun EM

  • KMID: 2378025
  • J Korean Acad Nurs.
  • 2003 Dec;33(7):1038-1046.
PURPOSE: The purpose of this study was to identify effects of the SP-6 acupressure on dysmenorrhea, and level of cortisol, epinephrine and norepinephrine in the college students. METHOD: Data were...
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The Effect of Intradermal Norepinephrine on Allodynia in a Neuropathic Pain Rat Model

Hwang JH, Choi DK, Kang HJ, Kim YK, Park JY

BACKGROUND: A spinal nerve ligation (SNL) injury may produce a neuropathic pain syndrome that includes tactile allodynia. This pain state may be diminished by sympathectomy. Intradermal (I.D.) injection...
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Effect of Ca2+-channel Blockers on Norepinephrine Release in the Rat Hippocampal Slice and Synaptosome

Kim SW, Jung KY, Choi BK

  • KMID: 1614995
  • Korean J Physiol Pharmacol.
  • 2002 Apr;6(2):87-92.
The aim of this study was to investigate the role of Ca2+-channel blockers in norepinephrine (NE) release from rat hippocampus. Slices and synaptosomes were incubated with [3H]-NE and the releases...
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Characterization of Norepinephrine Release in Rat Posterior Hypothalamus Using in vivo Brain Microdialysis

Sung KW, Kim SY, Kim ON, Lee SB

  • KMID: 1614852
  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):9-14.
In the present study, we used the microdialysis technique combined with high performance liquid chromatography (HPLC) and electrochemical detection to measure the extracellular levels of norepinephrine (NE) in the posterior...
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The Effects of Selective Norepinephrine Reuptake Inhibitors (SNRIs) on the Urethral Pressure

Bae JH, Moon DG, Lee JG

  • KMID: 2292322
  • Korean J Urol.
  • 2001 Jun;42(6):657-662.
PURPOSE: This study was performed to identify the effects of selective norepinephrine reuptake inhibitor (SNRI, venlafaxine) on the urethral perfusion pressure (UPP) and also to assess its therapeutic potentials for...
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The Effect of Low-dose Dopamine on Splanchnic and Renal Blood Flow in Patients with Septic Shock under the Treatment of Norepinephrine

Ahn JJ, Kim TH, Lee KM, Shim TS, Lim CM, Lee SD, Kim WS, Kim DS, Kim WD, Koh Y

  • KMID: 2228667
  • Korean J Crit Care Med.
  • 2001 Jun;16(1):36-41.
BACKGROUND: Norepinephrine, which is frequently administered as a vasopressor to the patients with septic shock, can decrease splanchnic and renal blood flows and aggravate splanchnic and renal ischemia. The low-dose...
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Effects of Norepinephrine on the Mechanoreceptors of the Urinary Bladder in the Cat

Oh HJ, Kang YJ, Min SS, Hwang JM, Lee SE, Yoon YW, Han HC, Hong SK

BACKGROUND: Recent findings suggest that a coupling between the somatic and sympathetic nervous system is critical not only for the development but also for the maintenance of pain behavioral changes....
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The Effect of Norepinephrine on Blood Pressure and Blood Flow of the Brachial and Femoral Arteries

Kim JH, Park YH, Nam SB, Hong YW, Seo MS, Kwak YL

BACKGROUND: Arterial pressure is the most commonly utilized guideline for the management of critically ill patients. However, the site of arterial pressure monitoring can impact the observed pressure. In patients...
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The Effects of Phenylephrine and Norepinephrine on Systemic and Pulmonary Hemodynamics in Patients with Pulmonary Hypertension

Kim JH, Nam SB, Park WS, Park HJ, Hong YW, Kwak YL

BACKGROUND: It is difficult to choose the appropriate drug when hypotension develops in patients with pulmonary hypertension (PH). There is no known drug to increase the systemic blood pressure...
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