J Korean Acad Conserv Dent.  2010 Jul;35(4):238-245. 10.5395/JKACD.2010.35.4.238.

Pulp tissue regeneration and root formation of permanent teeth with pulpal/periapical deseases

• Yoo YJ
• Baek SH
• Son HH

• KMID: 2176376
• DOI: http://doi.org/10.5395/JKACD.2010.35.4.238

Abstract

Numerous cases about additional growth of roots or pulp tissue regeneration by using various intracanal medicaments in immature permanent teeth with periapical or pulpal disease have been reported. The underlying mechanism has not been clearly delineated, but it has been widely accepted that undifferentiated mesenchymal cells and stem cells are involved. Moreover, the growth and deposition of osteoid or cementoid tissues have been observed in regenerated pulp and roots. This new and non-invasive treatment has brightened the future of endodontics, and enlarged the vision of regenerative root canal treatment with multi-potent stem cells and various tissue engineering techniques.

Keyword

Revascularization; Pulp tissue regeneration; Root formation; Tri-antibiotic paste; Tissue engineering

MeSH Terms

Dental Pulp Cavity
Endodontics
Regeneration
Stem Cells
Tissue Engineering
Tooth
Vision, Ocular