Intest Res.  2015 Jul;13(3):191-192. 10.5217/ir.2015.13.3.191.

Is Long-Term Therapy With Thiopurines Effective for Maintaining Remission in Patients With Moderate-To-Severe Ulcerative Colitis?

• Jeon SR
• Kim WH

• KMID: 2174459
• DOI: http://doi.org/10.5217/ir.2015.13.3.191

Abstract

No abstract available.

MeSH Terms

Colitis, Ulcerative*
Humans

Reference

1. Gisbert JP, Linares PM, McNicholl AG, Maté J, Gomollón F. Meta-analysis: the efficacy of azathioprine and mercaptopurine in ulcerative colitis. Aliment Pharmacol Ther. 2009; 30:126–137. PMID: 19392869.

2. Timmer A, McDonald JW, Macdonald JK. Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis. Cochrane Database Syst Rev. 2007; CD000478. DOI: 10.1002/14651858.CD000478.pub2. Published online 24 January 2007. PMID: 17253451.

3. Yamada S, Yoshino T, Matsuura M, et al. Efficacy and safety of long-term thiopurine maintenance treatment in Japanese patients with ulcerative colitis. Intest Res. 2015; 13:250–258.

4. Frøslie KF, Jahnsen J, Moum BA, Vatn MH. IBSEN Group. Mucosal healing in inflammatory bowel disease: results from a Norwegian population-based cohort. Gastroenterology. 2007; 133:412–422. PMID: 17681162.

5. Kim JH, Cheon JH, Kim TI, Kim WH. A survey of actual clinical practice patterns in the treatment of inflammatory bowel disease in Korea. Intest Res. 2009; 7:79–85.

6. Chande N, Tsoulis DJ, MacDonald JK. Azathioprine or 6-mercaptopurine for induction of remission in Crohn's disease. Cochrane Database Syst Rev. 2013; 4:CD000545. DOI: 10.1002/14651858.CD000545.pub4. Published online 30 April 2013. PMID: 23633304.

7. Park SK, Yang SK, Ye BD, et al. The long-term efficacy of azathioprine in steroid-dependent ulcerative colitis. Scand J Gastroenterol. 2013; 48:1386–1393. PMID: 24164382.

8. Hibi T, Naganuma M, Kitahora T, Kinjyo F, Shimoyama T. Low-dose azathioprine is effective and safe for maintenance of remission in patients with ulcerative colitis. J Gastroenterol. 2003; 38:740–746. PMID: 14505127.

9. Chaparro M, Ordás I, Cabré E, et al. Safety of thiopurine therapy in inflammatory bowel disease: long-term follow-up study of 3931 patients. Inflamm Bowel Dis. 2013; 19:1404–1410. PMID: 23665964.

10. Gearry RB, Barclay ML, Burt MJ, Collett JA, Chapman BA. Thiopurine drug adverse effects in a population of New Zealand patients with inflammatory bowel disease. Pharmacoepidemiol Drug Saf. 2004; 13:563–567. PMID: 15317038.